Q
Qian Ma
Publications - 5
Citations - 8
Qian Ma is an academic researcher. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 1, co-authored 5 publications receiving 8 citations.
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Journal ArticleDOI
Metabolic modulation of synaptic failure and thalamocortical hypersynchronization with preserved consciousness in Glut1 deficiency
Karthik Rajasekaran,Qian Ma,Levi B. Good,Gauri Kathote,Vikram Jakkamsetti,Peiying Liu,Adrian Avila,Sharon Primeaux,Julio Enciso Alva,Kia H. Markussen,Isaac Marin-Valencia,Deepa Sirsi,Peter M. S. Hacker,Matthew S. Gentry,Jianzhong Su,Hanzhang Lu,Juan M. Pascual +16 more
TL;DR: Electroencephalography in G1D individuals revealed nutrition time-dependent seizure oscillations often associated with preserved volition despite electrographic generalization and uniform average oscillation duration and periodicity, suggesting increased facilitation of an underlying neural loop circuit.
Journal ArticleDOI
Identification of Glucose Transport Modulators In Vitro and Method for Their Deep Learning Neural Network Behavioral Evaluation in Glucose Transporter 1–Deficient Mice
Gauri Kathote,Qian Ma,Gustavo Angulo,Hong Chen,Vikram Jakkamsetti,Aksharkumar Dobariya,Levi B. Good,Bruce A. Posner,Jason Y. Park,Juan M. Pascual +9 more
TL;DR: In this article , a gait testing platform for deep learning neural network analysis of drug impact on Glut1-deficient mouse locomotion is presented. But, the method is limited to a G1D mouse model that replicates the ataxia and other manifestations cardinal to the human disorder.
Posted ContentDOI
Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)
Aksharkumar Dobariya,Debra S. Douglass,Tarek Y. El Ahmadieh,Levi B. Good,Vikram Jakkamsetti,Gauri Kathote,Gustavo Angulo,Qian Ma,Ronnie J Brown,M. Dunbar,John M. Shelton,Bret M. Evers,Ulrike Hoffmann,Amy E. Hackmann,Bruce E. Mickey,Matthias Peltz,Michael E. Jessen,Juan M. Pascual +17 more
TL;DR: In this paper , a modified aorta or brachiocephalic artery was used to deliver full extracorporeal pulsatile circulatory control (EPCC) to the head of a pig.
Posted ContentDOI
Genetic influences on motor learning and superperformance mutants revealed by random mutational survey of mouse locomotion
TL;DR: In this paper , the motor effects of 36,444 non-synonymous coding/splicing mutations induced in the germline of C57BL/6J mice with N-ethyl-N-nitrosourea by measuring changes in the performance of repetitive rotarod trials while blinded to genotype.
Posted ContentDOI
Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations
Levi B. Good,Ana G. Hernandez-Reynoso,Qian Ma,Gustavo Angulo,Aksharkumar Dobariya,Stuart F. Cogan,Joseph J. Pancrazio,Juan M. Pascual,Vikram Jakkamsetti +8 more
TL;DR: In this article , the authors used mouse thalamocortical slices on multielectrode arrays and characterized spontaneous 2-4 Hz oscillations and less frequent 30-60 Hz or gamma oscillations under nearphysiological bath glucose concentration.