Q
Qiangqiang Peng
Researcher at East China University of Science and Technology
Publications - 4
Citations - 159
Qiangqiang Peng is an academic researcher from East China University of Science and Technology. The author has contributed to research in topics: Yeast & Pichia pastoris. The author has an hindex of 3, co-authored 3 publications receiving 83 citations.
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Journal ArticleDOI
Engineered monoculture and co-culture of methylotrophic yeast for de novo production of monacolin J and lovastatin from methanol.
Yiqi Liu,Xiaohu Tu,Qin Xu,Chenxiao Bai,Chuixing Kong,Qi Liu,Jiahui Yu,Qiangqiang Peng,Xiangshan Zhou,Yuanxing Zhang,Menghao Cai +10 more
TL;DR: This study provides an alternative method for production of monacolin J and lovastatin and reveals the potential of a methylotrophic yeast to produce complicated pharmaceuticals from methanol.
Journal ArticleDOI
Engineered ethanol-driven biosynthetic system for improving production of acetyl-CoA derived drugs in Crabtree-negative yeast.
Yiqi Liu,Chenxiao Bai,Qi Liu,Qin Xu,Zhilan Qian,Qiangqiang Peng,Jiahui Yu,Mingqiang Xu,Xiangshan Zhou,Yuanxing Zhang,Menghao Cai +10 more
TL;DR: This study provides a new paradigm for facilitating the high-yield production of acetyl-CoA derived pharmaceuticals and value-added molecules by constructing a new biosynthetic system based on a Crabtree-negative yeast, which grew exceptionally on ethanol and assimilated ethanol directly in cytosol to acetyl -CoA.
Journal ArticleDOI
Heterologous pathway assembly reveals molecular steps of fungal terreic acid biosynthesis
Chuixing Kong,Hezhou Huang,Ying Xue,Yiqi Liu,Qiangqiang Peng,Qi Liu,Qin Xu,Qiaoyun Zhu,Ying Yin,Xiangshan Zhou,Yuanxing Zhang,Menghao Cai +11 more
TL;DR: The individual reactions of terreic acid biosynthesis were determined by stepwise pathway assembly in a heterologous host on the basis of previous knockout studies in a native host, Aspergillus terreus, and the previously unknown function of AtD was identified as cyclooxygenation.
Journal ArticleDOI
A programmable high-expression yeast platform responsive to user-defined signals
Qi Liu,Lili Song,Qiangqiang Peng,Qiaoyun Zhu,Xiaona Shi,Mingqiang Xu,Qiyao Wang,Yuanxing Zhang,Menghao Cai +8 more
TL;DR: A programmable high-expression yeast platform, SynPic-X, which responds to defined signals and is broadly applicable, and provides opportunities for protein production in customizable yeast hosts with high expression and regulatory flexibility.