Q
Qing Chang
Publications - 2
Citations - 58
Qing Chang is an academic researcher. The author has contributed to research in topics: Binding site & Insulin receptor. The author has an hindex of 2, co-authored 2 publications receiving 57 citations.
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Journal ArticleDOI
A Human Monoclonal Antibody against Insulin-Like Growth Factor-II Blocks the Growth of Human Hepatocellular Carcinoma Cell Lines In vitro and In vivo
Daniel T. Dransfield,Edward H. Cohen,Qing Chang,Lindsay G. Sparrow,John D. Bentley,Olan Dolezal,Xiaowen Xiao,Thomas S. Peat,Janet Newman,Patricia A. Pilling,Tram Phan,Ilka Priebe,Gemma V. Brierley,Niksa Kastrapeli,Kris Kopacz,Diana Martik,Dina Wassaf,Douglas Rank,Greg Conley,Yan Huang,Timothy E. Adams,Leah J. Cosgrove +21 more
TL;DR: DX-2647 inhibited IGF-II and, to a lesser extent, IGF-I–induced receptor tyrosine phosphorylation, cellular proliferation, and both anch Anchorage-dependent and anchorage-independent colony formation in various cell lines.
Journal ArticleDOI
Identification and characterization of a human monoclonal antagonistic antibody AL-57 that preferentially binds the high-affinity form of lymphocyte function-associated antigen-1
Lili Huang,Motomu Shimaoka,Isaac J. Rondon,Illa Roy,Qing Chang,Melody Po,Daniel T. Dransfield,Robert Charles Ladner,Albert S.B. Edge,Azucena Salas,Clive R. Wood,Timothy A. Springer,Edward H. Cohen +12 more
TL;DR: Results indicate that specifically targeting the HA I domain is sufficient to inhibit LFA‐1‐mediated, adhesive functions, and represents a therapeutic candidate for treatment of inflammatory and autoimmune diseases.