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Qing-Quan Wu

Researcher at Nanjing Medical University

Publications -  11
Citations -  961

Qing-Quan Wu is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Chemoradiotherapy & Carcinoma. The author has an hindex of 9, co-authored 11 publications receiving 879 citations.

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Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarker for diagnosis of esophageal squamous cell carcinoma.

TL;DR: ESCC-related lncRNAs were detectable and stable in plasma of cancer patients, and derived largely from ESCC tumor cells, and the combination of POU3F3 and SCCA was more efficient for ESCC detection, in particular for early tumor screening.
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Upregulation of the long non-coding RNA HOTAIR promotes esophageal squamous cell carcinoma metastasis and poor prognosis.

TL;DR: HOTAIR is a novel molecule involved in both ESCC progression and prognosis and full elucidation of HOTAIR functionality relevant to ESCC may open avenues for the use of lncRNAs in identification of novel drug targets and therapies for ESCC and other prevalent cancers.
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Long noncoding RNA SPRY4-IT1 is upregulated in esophageal squamous cell carcinoma and associated with poor prognosis.

TL;DR: SPRY4-IT1 is a novel molecule involved in ESCC progression, which may provide a potential prognostic biomarker and a potential target for therapeutic intervention.
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Upregulation of the long noncoding RNA PCAT-1 correlates with advanced clinical stage and poor prognosis in esophageal squamous carcinoma

TL;DR: High expression of PCAT-1 was specifically correlated with invasion of cancer tissues, metastasis of lymph node, and advanced tumor stage of ESCC, indicating a potential diagnostic target in ESCC patients.
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Association of decreased expression of long non-coding RNA LOC285194 with chemoradiotherapy resistance and poor prognosis in esophageal squamous cell carcinoma

TL;DR: Decreased expression of LOC285194 could serve as a molecular marker to predict the clinical outcome of ESCC patients after surgery, and select patients who would benefit from preoperative CRT.