Q
Qingxi Yue
Researcher at Chinese Academy of Sciences
Publications - 5
Citations - 122
Qingxi Yue is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & CYP3A4. The author has an hindex of 3, co-authored 3 publications receiving 88 citations.
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Journal ArticleDOI
Pungent ginger components modulates human cytochrome P450 enzymes in vitro
TL;DR: 6-, 8-, and 10-gingerol suppress human cytochrome P450 activity, while 8- and10-gingers inhibit CYP3A4 expression, which may have an implication for the use of ginger or ginger products when combined with therapeutic drugs that are metabolized by cyto Chrome P450 enzymes.
Journal ArticleDOI
Dihydroartemisinin selectively inhibits PDGFRα-positive ovarian cancer growth and metastasis through inducing degradation of PDGFRα protein.
Xiaoguang Li,Qian Ba,Yanling Liu,Qingxi Yue,Peizhan Chen,Jingquan Li,Haibing Zhang,Hao Ying,Qiurong Ding,Haiyun Song,Hong Liu,Ruiwen Zhang,Hui Wang,Hui Wang +13 more
TL;DR: Dihydroartemisinin, one of the most active derivatives of ArtemisinIn, directly targets platelet-derived growth factor receptor-alpha (PDGFRα) to inhibit ovarian cancer cell growth and metastasis and shed high light on future development of novel Artemisinin-based targeted therapy.
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Artemisinin rewires the protein interaction network in cancer cells: network analysis, pathway identification, and target prediction
TL;DR: An analysis based on biological networks provides a deeper understanding of the molecular mechanisms of action of artemisinins and will contribute to the development and application of this class of compounds in cancer treatment.
Journal ArticleDOI
Ejiao ameliorates lipopolysaccharide-induced pulmonary inflammation via inhibition of NFκB regulating NLRP3 inflammasome and mitochondrial ROS.
Qingxi Yue,Wen Zhang,Shumeng Lin,Tiansheng Zheng,Yaqin Hou,Yanfei Zhang,Ziye Li,Kai Yin Wang,Liduo Yue,Baigenzhin Abay,Ming Li,Lihong Fan +11 more
TL;DR: Wang et al. as discussed by the authors showed Ejiao had a protective effect against LPS-elicited inflammatory lung epithelial Beas 2B cells (LILEB 2B).
Journal ArticleDOI
Amygdalin Induced Mitochondria-Mediated Apoptosis of Lung Cancer Cells via Regulating NF[Formula: see text]B-1/NF[Formula: see text]B Signaling Cascade in Vitro and in Vivo.
Shumeng Lin,Jing Wen,Xiao Xu,Jia-min Shi,Wen Zhang,Tiansheng Zheng,Yaqin Hou,Yanfei Zhang,Zi-wei Li,Kai Wang,Jing Jin,Liduo Yue,Baigenzhin Abay,Ming Li,Qingxi Yue,Lihong Fan +15 more
TL;DR: Amygdalin might be a potential activator of NF, which sheds more light on the molecular mechanism of anticancer effects of amygdalin, which warrants its development as a therapy for lung cancer.