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Qinong Ye
Researcher at Dalian Medical University
Publications - 57
Citations - 1808
Qinong Ye is an academic researcher from Dalian Medical University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 20, co-authored 40 publications receiving 1423 citations.
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Journal ArticleDOI
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Ling Li,Yingchun Liang,Lei Kang,Yang Liu,Shan Gao,Siyu Chen,Ying Li,Wenye You,Qian Dong,Tian Hong,Zhifeng Yan,Shuai Jin,Tao Wang,Wei Zhao,Haixing Mai,Jun Huang,Xiao Han,Quanbo Ji,Qi Song,Chao Yang,Shixin Zhao,Xiaojie Xu,Qinong Ye +22 more
TL;DR: It is shown that transcription factor SIX1 directly increases the expression of many glycolytic genes, promoting the Warburg effect and tumor growth in vitro and in–vivo.
Journal ArticleDOI
Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
Xiaojie Xu,Zhongyi Fan,Lei Kang,Juqiang Han,Chengying Jiang,Xiaofei Zheng,Ziman Zhu,Huabo Jiao,Jing Lin,Kai Jiang,Lihua Ding,Hao Zhang,Long Cheng,Hanjiang Fu,Song Yi,Ying Jiang,Jiahong Liu,Rongfu Wang,Nan Du,Qinong Ye +19 more
TL;DR: It is reported that miR-148a is repressed by hepatitis B virus (HBV) X protein (HBx) to promote cancer growth and metastasis in a mouse model of hepatocellular carcinoma (HCC).
Journal ArticleDOI
miR-30a-5p suppresses breast tumor growth and metastasis through inhibition of LDHA-mediated Warburg effect.
Ling Li,Lei Kang,Wei Zhao,Yingying Feng,Wenpeng Liu,Tao Wang,Haixing Mai,Jun Huang,Siyu Chen,Yingchun Liang,Juqiang Han,Xiaojie Xu,Qinong Ye +12 more
TL;DR: Through inhibition of LDHA, miR-30a-5p dampens glycolysis by decreasing glucose uptake, lactate production, ATP generation, and extracellular acidification rate (ECAR), and increasing oxygen consumption rate (OCR) in breast cancer cells.
Journal ArticleDOI
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-β–like signaling pathway
Lihua Ding,Zhao-yun Wang,Jinghua Yan,Xiao Yang,Aijun Liu,Weiyi Qiu,Jianhua Zhu,Juqiang Han,Hao Zhang,Jing Lin,Long Cheng,Xi Qin,Chang Niu,Bin Yuan,Xiaohui Wang,Cui Zhu,Yan Zhou,Jiezhi Li,Haifeng Song,Cuifen Huang,Qinong Ye +20 more
TL;DR: It is reported that FHL1, FHL2, and FHL3 physically and functionally interact with Smad2, Smad3, and Smad4, important regulators of cancer development and progression, in a TGF-beta-independent manner.
Journal ArticleDOI
The EGFR/miR-338-3p/EYA2 axis controls breast tumor growth and lung metastasis.
Yingchun Liang,Xiaojie Xu,Tao Wang,Ying Li,Wenye You,Jing Fu,Yang Liu,Shuai Jin,Quanbo Ji,Wei Zhao,Qi Song,Ling Li,Tian Hong,Junjian Huang,Zhaohui Lyu,Qinong Ye +15 more
TL;DR: The data suggest that the miR-338-3p/EYA2 axis contributes to EGFR-mediated tumor growth and lung metastasis and that combination therapy targeting EGFR/miR- 338-3 p/EYa2 axis may be a promising way to treat patients with metastatic cancer.