Qiong Zhao

TL;DR: It is shown that MAP1B is highly expressed in the spiral ganglion neurons in the mouse cochlea and involvement in hearing was confirmed by audiometric evaluation of Map1b heterozygous KO mice, and dysfunctions of spiral ganglia induced by MAP1b deficiency caused hearing loss.

TL;DR: It is reported that acute myeloid leukemia (AML) induces MSCs towards an adipogenic differentiation propensity, which suggests complex interactions of leukemia with microenvironment components and indicates novel therapeutic strategies based on the targeting of exosome‐based AML cells‐MSCs communication.

TL;DR: Results indicate that HARS2 overexpression corrects the mitochondrial dysfunction caused by the tRNAHis mutation and provide critical insights into the pathophysiology of mitochondrial disease and represent a step toward improved therapeutic interventions for mitochondrial disorders.

TL;DR: It is reported that acute myeloid leukemia (AML) induces MSCs towards an adipogenic differentiation propensity, and the data show that AML‐educated M SCs tend to differentiate into adipocytes contributing to disease progression, which suggests complex interactions of leukemia with microenvironment components.

TL;DR: In this article, the authors reported that Mtu1 defects are correlated with reduced osteogenic differentiation and reduced mitochondrial ATP production, leading to respiratory deficiencies and reduced mitochondria ATP production.