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Qiuhong Li
Researcher at University of Florida
Publications - 97
Citations - 5442
Qiuhong Li is an academic researcher from University of Florida. The author has contributed to research in topics: Angiotensin II & Renin–angiotensin system. The author has an hindex of 36, co-authored 93 publications receiving 4624 citations. Previous affiliations of Qiuhong Li include University of Pennsylvania.
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Journal ArticleDOI
High-efficiency Transduction of the Mouse Retina by Tyrosine-mutant AAV Serotype Vectors
Hilda Petrs-Silva,Astra Dinculescu,Qiuhong Li,Seok-Hong Min,Vince A. Chiodo,Jijing Pang,Li Zhong,Sergei Zolotukhin,Arun Srivastava,Alfred S. Lewin,William W. Hauswirth +10 more
TL;DR: Efficient transduction of the ganglion cell layer by AAV serotype 8 or 9 mutant vectors is shown, thus providing additional tools besides AAV2 for targeting these cells, which have a great potential for future therapeutic applications for retinal degenerations and ocular neovascular diseases.
Journal ArticleDOI
Brain Microglial Cytokines in Neurogenic Hypertension
Peng Shi,Carlos Diez-Freire,Joo Yun Jun,Yanfei Qi,Michael J. Katovich,Qiuhong Li,Srinivas Sriramula,Joseph Francis,Colin Sumners,Mohan K. Raizada +9 more
TL;DR: It is indicated that angiotensin II induced hypertension involves activation of microglia and increases in proinflammatory cytokines in the PVN, which has significant implications on the development of innovative therapeutic strategies for the control of neurogenic hypertension.
Journal ArticleDOI
Gene therapy for red–green colour blindness in adult primates
Katherine Mancuso,William W. Hauswirth,Qiuhong Li,Thomas B. Connor,James A. Kuchenbecker,Matthew C. Mauck,Jay Neitz,Maureen Neitz +7 more
TL;DR: It is shown that the addition of a third opsin in adult red–green colour-deficient primates was sufficient to produce trichromatic colour vision behaviour, providing a positive outlook for the potential of gene therapy to cure adult vision disorders.
Journal ArticleDOI
Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina
Hilda Petrs-Silva,Astra Dinculescu,Qiuhong Li,Wen-Tao Deng,Jijing Pang,Seok-Hong Min,Vince A. Chiodo,Andy W. Neeley,Lakshmanan Govindasamy,Antonette Bennett,Mavis Agbandje-McKenna,Li Zhong,Baozheng Li,Giridhara R. Jayandharan,Arun Srivastava,Alfred S. Lewin,William W. Hauswirth +16 more
TL;DR: The transduction characteristics of AAV2 vectors containing combinations of multiple tyrosine to phenylalanine mutations in seven highly conserved surface-exposed capsid tyrosines following subretinal or intravitreal delivery in adult mice were evaluated.
Journal ArticleDOI
Restoration of cone vision in a mouse model of achromatopsia
John J. Alexander,Yumiko Umino,Drew Everhart,Bo Chang,Seok Hong Min,Qiuhong Li,Adrian M. Timmers,Norman L. Hawes,Jijing Pang,Robert B. Barlow,William W. Hauswirth +10 more
TL;DR: It is shown that it is possible to target cones and rescue both the cone-mediated electroretinogram response and visual acuity in the Gnat2 cpfl3 mouse model of achromatopsia using adeno-associated virus (AAV) gene therapy.