Quancheng Kan

TL;DR: This study is the first to characterise gut microbiome in patients with HCC and to report the successful diagnosis model establishment and cross-region validation of microbial markers for HCC.

TL;DR: In vitro and in vivo investigations demonstrate that the combination of chemotherapy and chemodynamic therapy achieves excellent anticancer efficacy, and systemic toxicity faced by platinum‐based drugs is avoided through this nanoformulation.

TL;DR: A number of novel strategies used by small-molecule inhibitors to prevent the development of multidrug resistance hold great promise for prolonging the efficacy of chemotherapy treatment and improving the clinical outcomes of patients with cancers that are susceptible to MDR development.

TL;DR: Wang et al. as discussed by the authors investigated the potential of the oral microbiome as a non-invasive biomarker for COVID-19 and explored correlations between the microbiome and lipid profile by collecting and sequencing 392 tongue-coating samples, 172 faecal samples and 155 serum samples from Central China and East China.

TL;DR: New strategies to overcome MDR with more potent and specific Pgp inhibitors, targeting CSCs and ncRNA, modulating autophagy signaling pathway, and targeting tumor heterogeneity are evaluated.