Lignocellulose is a kind of renewable bioresource containing abundant polysaccharides, which can be used for biochemicals and biofuels production. However, the complex structure hinders the final efficiency of lignocellulosic biorefinery. This review comprehensively summarizes the hydrolases and typical microorganisms for lignocellulosic degradation. Moreover, the commonly used bioprocesses for lignocellulosic biorefinery are also discussed, including separated hydrolysis and fermentation, simultaneous saccharification and fermentation and consolidated bioprocessing. Among these methods, construction of microbial co-culturing systems via consolidated bioprocessing is regarded as a potential strategy to efficiently produce biochemicals and biofuels, providing theoretical direction for constructing efficient and stable biorefinery process system in the future.

Challenges and Future Perspectives of Promising Biotechnologies for Lignocellulosic Biorefinery

Contemporary proteomic research on lignocellulosic enzymes and enzymolysis: A review

Synthesis of magnetic nanoparticles functionalized with histidine and nickel to immobilize His-tagged enzymes using β-galactosidase as a model.

Sesquiterpene lactones-rich fraction from Aucklandia lappa Decne. alleviates dextran sulfate sodium induced ulcerative colitis through co-regulating MAPK and Nrf2/Hmox-1 signaling pathway.

As a new environmentally friendly and sustainable green solvent, deep eutectic solvent (DES) was considered to be the most suitable alternative solvent for ionic liquids, with wide application. In ...

Magnetic nanoparticles prepared in natural deep eutectic solvent for enzyme immobilisation

Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through Keap1-mediated Nrf2 ubiquitination degradation.

Production, immobilization and characterization of beta-glucosidase for application in cellulose degradation from a novel Aspergillus versicolor.

Abstract Plants that belong to the genus Taraxacum are commonly referred to as dandelions; these are some of the most evolved plants in the Asteraceae, with more than 2000 species distributed worldwide. Dandelions not only include medicinal plants but also rubber-producing plants. Recent advances in biotechnology and the growing demand for dandelions have increased research attention toward dandelions. Owing to the availability of the whole genome sequence of Taraxacum kok-saghyz, and Taraxacum mongolicum (accession no. GWHBCHF00000000 and GWHAAAA00000000), and large transcriptome and metabolome databases for T. kok-saghyz, Taraxacum officinale, T. mongolicum, and Taraxacum antungense (accession no. PRJNA378120, PRJEB48186, PRJNA897666, and PRJNA578773), significant progress has been made in understanding the biosynthesis and regulatory mechanisms of phenolic acids, flavonoids, terpenoids, rubber, and other bioactive compounds. This review focuses on Taraxacum spp.; specifically, We describe the following: (1) the recent results of genetic transformation systems, (2) biosynthetic pathways of bioactive compounds and natural rubber, (3) cross-talk in the biosynthesis of different secondary metabolites, (4) the relevance of the environment and the reproductive mode of dandelions in secondary metabolite biosynthesis, and (5) future research directives for dandelions. This review also lays the foundation for further research on other medicinal and edible plants.

Understanding the biosynthesis and regulatory mechanisms of bioactive compounds in Taraxacum species (dandelions), a model system for natural rubber, food, and medicinal plant biology

Qun Liu

Papers

Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through Keap1-mediated Nrf2 ubiquitination degradation.

Production, immobilization and characterization of beta-glucosidase for application in cellulose degradation from a novel Aspergillus versicolor.

Understanding the biosynthesis and regulatory mechanisms of bioactive compounds in Taraxacum species (dandelions), a model system for natural rubber, food, and medicinal plant biology

Nano Drug Delivery Systems: Effective Therapy Strategies to Overcome Multidrug Resistance in Tumor Cells