R
R. Duncan Hite
Researcher at University of Cincinnati
Publications - 50
Citations - 6642
R. Duncan Hite is an academic researcher from University of Cincinnati. The author has contributed to research in topics: Lung injury & Pulmonary surfactant. The author has an hindex of 21, co-authored 46 publications receiving 5684 citations. Previous affiliations of R. Duncan Hite include Wake Forest University & Cleveland Clinic Lerner Research Institute.
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Journal ArticleDOI
Relationship between the inflammation and coagulation pathways in patients with severe sepsis: implications for therapy with activated protein C.
TL;DR: A phase III clinical trial has now demonstrated reduced mortality in patients with severe sepsis receiving activated protein C.
Journal ArticleDOI
Point: should positive end-expiratory pressure in patients with ARDS be set on oxygenation? Yes.
Russell R. Miller,Russell R. Miller,Neil R. MacIntyre,R. Duncan Hite,Jonathon D. Truwit,Roy G. Brower,Alan H. Morris,Alan H. Morris +7 more
TL;DR: This work was supported in part by the National Institutes of Health, and the authors have reported to CHEST the following conflicts of interest.
Journal ArticleDOI
Postexposure Liponucleotide Prophylaxis and Treatment Attenuates Acute Respiratory Distress Syndrome in Influenza-infected Mice.
Lucia E. Rosas,Lauren M. Doolittle,Lisa M Joseph,Hasan El-Musa,Michael Novotny,Judy M. Hickman-Davis,R. Duncan Hite,Ian C. Davis +7 more
TL;DR: The data show that liponucleotides act rapidly to reduce disease severity in mice with severe influenza-induced ARDS, and co-administration of CDP-diacylglycerol significantly enhanced the beneficial effects of C DP-choline and also modified the ATII cell lipidome.
Journal ArticleDOI
Implementation of Protocolized Care in ARDS Improves Outcomes.
Abhijit Duggal,Anupol Panitchote,Matthew Siuba,Sudhir Krishnan,Heather Torbic,Andrei Hastings,Omar Mehkri,Tarik Hanane,Umur Hatipoğlu,R. Duncan Hite,Eduardo Mireles-Cabodevila +10 more
TL;DR: ARDS protocol implementation was associated with improved survival and rate of adherence, and the median plateau pressure and tidal volume over the first 3 d decreased significantly after protocol implementation.