J
Jonathon D. Truwit
Researcher at Medical College of Wisconsin
Publications - 97
Citations - 5484
Jonathon D. Truwit is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Mechanical ventilation & ARDS. The author has an hindex of 35, co-authored 91 publications receiving 4658 citations. Previous affiliations of Jonathon D. Truwit include United States Department of Veterans Affairs & University of Virginia Health System.
Papers
More filters
Journal ArticleDOI
Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial
Alpha A. Fowler,Jonathon D. Truwit,R. Duncan Hite,Peter E. Morris,Christine DeWilde,Anna Priday,Bernard J. Fisher,Leroy R. Thacker,Ramesh Natarajan,Donald F. Brophy,Robin Sculthorpe,Rahul Nanchal,Aamer Syed,Jamie Sturgill,Greg S. Martin,Jonathan E. Sevransky,Markos Kashiouris,Stella Hamman,Katherine Egan,Andrei Hastings,Wendy Spencer,Shawnda Tench,Omar Mehkri,James Bindas,Abhijit Duggal,Jeanette Graf,Stephanie Zellner,Lynda Yanny,Catherine McPolin,Tonya Hollrith,David W. Kramer,Charles Ojielo,Tessa Damm,Evan Cassity,Aleksandra Wieliczko,Matthew S. Halquist +35 more
TL;DR: In this preliminary study of patients with sepsis and ARDS, a 96-hour infusion of vitamin C compared with placebo did not significantly improve organ dysfunction scores or alter markers of inflammation and vascular injury.
Journal ArticleDOI
Ventilator-Associated Pneumonia: Diagnosis, Treatment, and Prevention
TL;DR: Drawing conclusions that can be implemented in practice as well as an algorithm for the bedside clinician are provided and the controversies with regard to diagnostic tools and approaches, treatment plans, and prevention strategies are focused on.
Journal ArticleDOI
Rosuvastatin for Sepsis-Associated Acute Respiratory Distress Syndrome
Jonathon D. Truwit,Gordon R. Bernard,Jay S. Steingrub,Michael A. Matthay,Kathleen D. Liu,Timothy E Albertson,Roy G. Brower,Carl Shanholtz,Peter Rock,Ivor S. Douglas,Bennett P. deBoisblanc,Catherine L. Hough,R. Duncan Hite,B. Taylor Thompson +13 more
TL;DR: Rosuvastatin therapy did not improve clinical outcomes in patients with sepsis-associated ARDS and may have contributed to hepatic and renal organ dysfunction, and was not associated with an increased incidence of serum creatine kinase levels that were more than 10 times the upper limit of the normal range.
Journal ArticleDOI
Emphysema: Hyperpolarized Helium 3 Diffusion MR Imaging of the Lungs Compared with Spirometric Indexes—Initial Experience
Michael Salerno,Eduard E. de Lange,Talissa A. Altes,Jonathon D. Truwit,James R. Brookeman,John P. Mugler +5 more
TL;DR: Hyperpolarized (3)He diffusion MR imaging demonstrated potential for use in evaluating the global and regional severity of emphysema and whether apparent diffusion coefficients (ADCs) measured with MR imaging correlate with spirometric indexes.
Journal ArticleDOI
Acute kidney injury in patients with acute lung injury: Impact of fluid accumulation on classification of acute kidney injury and associated outcomes
Kathleen D. Liu,B. Taylor Thompson,Marek Ancukiewicz,Jay S. Steingrub,Ivor S. Douglas,Michael A. Matthay,Patrick Wright,Michael W. Peterson,Peter Rock,Robert C. Hyzy,Antonio Anzueto,Jonathon D. Truwit +11 more
TL;DR: Fluid management influences serum creatinine and therefore the diagnosis of acute kidney injury using Creatinine-based definitions, and patients who have acute kidneys injury before but not after adjusting for fluid balance have lower mortality rates.