Electrochemistry represents one of the most intimate ways of interacting with molecules. This review discusses advances in synthetic organic electrochemistry since 2000. Enabling methods and synthetic applications are analyzed alongside innate advantages as well as future challenges of electroorganic chemistry.

Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance

The preparation and transformation of heterocyclic structures have always been of great interest in organic chemistry. Electrochemical technique provides a versatile and powerful approach to the assembly of various heterocyclic structures. In this review, we examine the advance in relation to the electrochemical construction of heterocyclic compounds published since 2000 via intra- and intermolecular cyclization reactions.

Use of Electrochemistry in the Synthesis of Heterocyclic Structures.

Asymmetric catalysis at chiral metal surfaces.

The application of solid chiral catalysts for the enantioselective synthesis of chiral molecules is reviewed. An attempt has been made to discuss critically the scope and limitations of these catalytic systems and their value for the synthetic organic chemist. The different catalytic systems described in the literature are tabulated and the enantioselectivities observed for different reactions are summarized according to the functional group which is transformed. Conclusions concerning synthetic and commercial-scale applications and some ideas on the mode of action of chiral solid catalysts are presented.

Enantioselective synthesis using chiral heterogeneous catalysts.

Electrochemical reactions with protonations at equilibrium: Part VIII. The 2 e, 2H+ reaction (nine-member square scheme) for a surface or for a heterogeneous reaction in the absence of disproportionation and dimerization reactions

Stereochemistry of electroreductions of bromocyclopropanes: 1-asymmetric electrochemical synthesis by reduction at a mercury cathode in the presence of adsorbed alkaloïds

Electrochemical reduction of substituted pyridazines: a new access to activated pyrroles

On the electrochemical behaviour of Nifedipine and related compounds: instability of the reduction products in protic media

Electrochemical reduction of o-nitrophenylthioacetic derivatives. Production of 2H-1,4-benzothiazines

Aspect stereochimique de l'electroreduction de cyclenes actives. II. Reduction sur cathode de mercure des dicarboxy - 1,2 cyclopentene et cyclohexene et de leurs diesters methyliques: mecanisme et stereochimie☆

R. Hazard

Papers

Stereochemistry of electroreductions of bromocyclopropanes: 1-asymmetric electrochemical synthesis by reduction at a mercury cathode in the presence of adsorbed alkaloïds

Electrochemical reduction of substituted pyridazines: a new access to activated pyrroles

On the electrochemical behaviour of Nifedipine and related compounds: instability of the reduction products in protic media

Electrochemical reduction of o-nitrophenylthioacetic derivatives. Production of 2H-1,4-benzothiazines

Aspect stereochimique de l'electroreduction de cyclenes actives. II. Reduction sur cathode de mercure des dicarboxy - 1,2 cyclopentene et cyclohexene et de leurs diesters methyliques: mecanisme et stereochimie☆