R
R. K. Gupta
Researcher at St Bartholomew's Hospital
Publications - 32
Citations - 951
R. K. Gupta is an academic researcher from St Bartholomew's Hospital. The author has contributed to research in topics: Follicular lymphoma & Reed–Sternberg cell. The author has an hindex of 15, co-authored 31 publications receiving 944 citations.
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Journal ArticleDOI
High-Dose Therapy With Autologous Bone Marrow Support as Consolidation of Remission in Follicular Lymphoma: Long-Term Clinical and Molecular Follow-Up
John Apostolidis,R. K. Gupta,Demetrios Grenzelias,Peter Johnson,Vassiliki Pappa,Karin E. Summers,Ashiq Salam,K. Adams,Andrew Norton,J. A. L. Amess,Janet Matthews,Mike Bradburn,T. Andrew Lister,Ama Z. S. Rohatiner +13 more
TL;DR: It is confirmed that elimination of cells bearing the Bcl-2/IgH rearrangement is highly desirable and should be attempted in patients with follicular lymphoma after high-dose therapy, and there is no survival advantage compared with conventional treatment.
Journal ArticleDOI
Frequency of the Bcl-2/IgH Rearrangement in Normal Individuals: Implications for the Monitoring of Disease in Patients With Follicular Lymphoma
Karin E. Summers,Lindsey K. Goff,A. Gerry Wilson,R. K. Gupta,T. Andrew Lister,Jude Fitzgibbon +5 more
TL;DR: The presence of circulating Bcl-2/IgH+ cells, other than those derived from the malignant clone, could confound the detection and quantitation of minimal residual disease in patients with FL, particularly at low levels of tumor burden.
Journal ArticleDOI
The use of real-time quantitative polymerase chain reaction and comparative genomic hybridization to identify amplification of the REL gene in follicular lymphoma
Lindsey K. Goff,Michael J. Neat,Charles Crawley,Louise Jones,Emma Jones,T. Andrew Lister,R. K. Gupta +6 more
TL;DR: This study shows the usefulness of coupling CGH, for detecting recurring abnormalities, with the real-time PCR technique for rapid gene dosage quantification and confirms that the REL gene is a potential candidate in the pathogenesis of a particular subset of follicular lymphomas.
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ChlVPP/EVA Hybrid Versus the Weekly VAPEC-B Regimen for Previously Untreated Hodgkin’s Disease
John Radford,A. Z. S. Rohatiner,W. D. J. Ryder,David P Deakin,Tiziano Barbui,N. P. Lucie,Andrea Rossi,DJ Dunlop,Richard A Cowan,P. M. Wilkinson,R. K. Gupta,Roger D James,Jonathan Shamash,Jenny C. Chang,Derek Crowther,T. A. Lister +15 more
TL;DR: Apart from possibly in the best-prognosis group, where results are equivalent, ChlVPP/EVA hybrid produces significantly better FFP, EFS, and OS than VAPEC-B in patients with previously untreated Hodgkin's disease.
Journal ArticleDOI
Nodular type of lymphocyte predominant Hodgkin's disease. A clinical study of 50 cases
TL;DR: The diffuse variant of LP-HD is rare, having not been seen at St. Bartholomew's Hospital during this time period and showed a favourable course with presentation at an early stage, good response to treatment, late recurrences and remission duration other than the other subtypes of HD.