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R

R. K. Gupta

Researcher at St Bartholomew's Hospital

Publications -  32
Citations -  951

R. K. Gupta is an academic researcher from St Bartholomew's Hospital. The author has contributed to research in topics: Follicular lymphoma & Reed–Sternberg cell. The author has an hindex of 15, co-authored 31 publications receiving 944 citations.

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High-Dose Therapy With Autologous Bone Marrow Support as Consolidation of Remission in Follicular Lymphoma: Long-Term Clinical and Molecular Follow-Up

TL;DR: It is confirmed that elimination of cells bearing the Bcl-2/IgH rearrangement is highly desirable and should be attempted in patients with follicular lymphoma after high-dose therapy, and there is no survival advantage compared with conventional treatment.
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Frequency of the Bcl-2/IgH Rearrangement in Normal Individuals: Implications for the Monitoring of Disease in Patients With Follicular Lymphoma

TL;DR: The presence of circulating Bcl-2/IgH+ cells, other than those derived from the malignant clone, could confound the detection and quantitation of minimal residual disease in patients with FL, particularly at low levels of tumor burden.
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The use of real-time quantitative polymerase chain reaction and comparative genomic hybridization to identify amplification of the REL gene in follicular lymphoma

TL;DR: This study shows the usefulness of coupling CGH, for detecting recurring abnormalities, with the real-time PCR technique for rapid gene dosage quantification and confirms that the REL gene is a potential candidate in the pathogenesis of a particular subset of follicular lymphomas.
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ChlVPP/EVA Hybrid Versus the Weekly VAPEC-B Regimen for Previously Untreated Hodgkin’s Disease

TL;DR: Apart from possibly in the best-prognosis group, where results are equivalent, ChlVPP/EVA hybrid produces significantly better FFP, EFS, and OS than VAPEC-B in patients with previously untreated Hodgkin's disease.
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Nodular type of lymphocyte predominant Hodgkin's disease. A clinical study of 50 cases

TL;DR: The diffuse variant of LP-HD is rare, having not been seen at St. Bartholomew's Hospital during this time period and showed a favourable course with presentation at an early stage, good response to treatment, late recurrences and remission duration other than the other subtypes of HD.