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R K Lynn

Researcher at University of Oregon

Publications -  23
Citations -  918

R K Lynn is an academic researcher from University of Oregon. The author has contributed to research in topics: Metabolite & Valproic Acid. The author has an hindex of 14, co-authored 23 publications receiving 905 citations. Previous affiliations of R K Lynn include National Institutes of Health & The Graduate Center, CUNY.

Papers
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Journal ArticleDOI

Reye-like syndrome associated with valproic acid therapy†

N Gerber, +6 more
- 01 Jul 1979 - 
Journal Article

Disposition of valproic acid in the rat: dose-dependent metabolism, distribution, enterohepatic recirculation and choleretic effect.

R G Dickinson, +6 more
- 01 Dec 1979 - 
TL;DR: A specific gas chromatographic assay has been developed for measurement of valproic acid (VPA) and its major conjugated metabolites and sodium VPA caused a dose-dependent stimulation of bile flow, the magnitude and duration of which closely followed the blood concentration of VPA.
Journal ArticleDOI

Clinical eftects and pharmacokinetics of racemic methadone and its optical isomers

George D. Olsen, +5 more
- 01 Feb 1977 - 
TL;DR: D,l‐Methadone administeredfrequently for pain may have cumulative effects on respiratory control and ability to excrete a water load, and whole blood drug concentration correlated weil with respiratory depression and miosis for 1‐ and d, l‐methadones.
Journal ArticleDOI

Transmission of valproic acid (Depakene) across theplacenta: Half-life of the drug in mother and baby†

Dickinson Rg, +4 more
- 01 May 1979 - 
Journal ArticleDOI

Metabolism of bisazobiphenyl dyes derived from benzidine, 3,3'-dimethylbenzidine or 3,3'-dimethoxybenzidine to carcinogenic aromatic amines in the dog and rat.

R K Lynn, +11 more
- 01 Nov 1980 - 
TL;DR: Results from this study indicate that the metabolic conversion of bisazobiphenyl dyes, derived from benzidine and 3-3′-dimethyl- and 3,3″-dimethoxybenzidine, to carcinogenic aromatic amines is a general phenomenon and therefore with few exceptions should be anticipated for each member of this class of chemicals.