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R L DeLaPaz

Researcher at Harvard University

Publications -  10
Citations -  1265

R L DeLaPaz is an academic researcher from Harvard University. The author has contributed to research in topics: Positron emission tomography & Glycolysis. The author has an hindex of 8, co-authored 10 publications receiving 1246 citations.

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Glucose utilization of cerebral gliomas measured by [18F] fluorodeoxyglucose and positron emission tomography

TL;DR: A correlation between rate of glycolysis and malignancy in primary cerebral tumors is found and Cerebral cortical glucose utilization was often depressed in areas adjacent to or neurally connected to the tumor site, and there was focal irregular delta wave EEG activity in these areas.
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Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain

TL;DR: Five patients who had undergone radiation therapy for cerebral tumors and whose conditions were deteriorating were examined by means of positron emission tomography (PET) with [18F] fluorodeoxyglucose and the two cases of radiation necrosis were distinguished from the three recurrent tumors.
Journal Article

Glycolytic Rate (PET) and Contrast Enhancement (CT) in Human Cerebral Gliomas

TL;DR: A comparison of the glycolytic rate as determined by positron emission tomography with 18F-deoxyglucose (FDG) and cerebral contrast computed tomography (CT) was carried out in 72 cases of cerebral glioma, finding FDG-PET is more accurate than contrast CT in predicting tumor grade.
Journal Article

Positron Emission Tomographic Study of Suppression of Gray-Matter Glucose Utilization by Brain Tumors

TL;DR: PET scanning with [18F]-2-fluoro-2-deoxy-D-glucose (FDG) was used to study 59 patients with astrocytomas and three patients with other cerebral mass lesions, finding that this approach may become a useful tool for improved understanding of the clinical presentation of certain pathologic entities.
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Glucose metabolism in human gliomas: correspondence of in situ and in vitro metabolic rates and altered energy metabolism.

TL;DR: Human glioma-derived cell cultures adequately reflect the metabolic capacity of gliomas in situ and are significantly altered in several aspects of their glycolytic metabolism.