Barry H. Smith

TL;DR: A correlation between rate of glycolysis and malignancy in primary cerebral tumors is found and Cerebral cortical glucose utilization was often depressed in areas adjacent to or neurally connected to the tumor site, and there was focal irregular delta wave EEG activity in these areas.

TL;DR: Five patients who had undergone radiation therapy for cerebral tumors and whose conditions were deteriorating were examined by means of positron emission tomography (PET) with [18F] fluorodeoxyglucose and the two cases of radiation necrosis were distinguished from the three recurrent tumors.

TL;DR: Over 150 cases of central nervous system tumors have been studied with positron emission tomography using fluorine‐18‐labeled fluorodeoxyglucose (18FDG) as a tracer, showing a strong correlation of tumor grade with glycolytic rate and visual “hot spots” present in all high‐grade neoplasms and in only four low‐grade tumors.

TL;DR: The ability of FDG-PET scans to detect metabolic changes, not apparent on CT scans, in areas of the brain remote from the primary lesion is illustrated.

TL;DR: It is concluded that the maximum tolerable dose of BUdR is 650 to 700 mg/m2/12 hrs when given as a 2 week intermittent intravenous infusion and the major systemic toxicities are myelosuppression and a maculopapular skin rash.