R
R. Nash
Researcher at Cold Spring Harbor Laboratory
Publications - 3
Citations - 955
R. Nash is an academic researcher from Cold Spring Harbor Laboratory. The author has contributed to research in topics: Cell cycle & Cyclin-dependent kinase 1. The author has an hindex of 3, co-authored 3 publications receiving 940 citations.
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The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog.
TL;DR: A probable accessory function of the WHI1 activator is to assist recovery from alpha factor arrest; WHI 1‐1 mutant cells could not be permanently arrested by pheromone, consistent with a hyperactivation of division.
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The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation.
TL;DR: In Saccharomyces cerevisiae, several of the proteins involved in the Start decision have been identified; these include the Cdc28 protein kinase and three cyclin‐like proteins, Cln1, ClN2 and Cln3, and it is found that Cln 3 is a very unstable, low abundance protein.
Journal ArticleDOI
Characterization of G1 and mitotic cyclins of budding yeast
TL;DR: It has been known for a decade that in yeast, the CDC28 gene of Saccharomyces cerevisiae and the cdc2+ gene of SchizosacCharomyces pombe are needed at two points in their host's cell cycles: once in G1 phase, for commitment to division, and once again in mitosis.