R
R. Rubio Gonzalez
Researcher at University of Salamanca
Publications - 80
Citations - 789
R. Rubio Gonzalez is an academic researcher from University of Salamanca. The author has contributed to research in topics: Radical cyclization & Catalysis. The author has an hindex of 15, co-authored 80 publications receiving 727 citations.
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Journal ArticleDOI
Radicals from Epoxides. Intramolecular Addition to Aldehyde and Ketone Carbonyls
Alfonso Fernández-Mateos,E. M. Martin de la Nava,G. Pascual Coca,and A. Ramos Silvo,R. Rubio Gonzalez +4 more
TL;DR: The behavior of epoxy alcohols with titanocene chloride to afford saturated diols and epoxy esters that give unsaturated hydroxy esters are discussed in this paper.
Journal ArticleDOI
On the mechanism and kinetics of radical reactions of epoxyketones and epoxynitriles induced by titanocene chloride
Alfonso Fernández-Mateos,P. Herrero Teijón,L. Mateos Buron,R. Rabanedo Clemente,R. Rubio Gonzalez +4 more
TL;DR: The reactions of a series of epoxynitriles and epoxyketones induced by titanocene chloride have been studied and the role of Ti(III) is triple: a radical initiator (homolytic cleavage of oxirane), a Lewis acid (coordination to CN or C=O), and a terminator (reduction of iminyl or alkoxyl radicals).
Journal ArticleDOI
Outcomes of Estrogen Receptor Negative and Progesterone Receptor Positive Breast Cancer.
Melissa Chan,Martin C. Chang,R. Rubio Gonzalez,Belinda Lategan,Elvira del Barco,Francisco E. Vera-Badillo,Paula Quesada,Robyn Goldstein,Ignacio Cruz,Alberto Ocaña,Juan Jesús Cruz,Eitan Amir +11 more
TL;DR: The ER-/PgR+ phenotype is associated with higher grade with HER2 overexpression/amplification and occurs more commonly in younger women, suggesting this phenotype represents a group of more aggressive hormone receptor positive tumors.
Journal ArticleDOI
Radical Cyclization of Epoxynitriles Mediated by Titanocene Chloride
Alfonso Fernández-Mateos,L. Mateos Buron,R. Rabanedo Clemente,Ana I. Ramos Silvo,R. Rubio Gonzalez +4 more
TL;DR: In this article, the reductive radical cyclization of β-, γ-, δ- and e-epoxynitriles has been achieved using titanocene chloride, which was regioselective and afforded cyclic β-hydroxyketones in good yield.
Journal ArticleDOI
Ti(III)-promoted cyclizations. Application to the synthesis of (E)-endo-bergamoten-12-oic acids. Moth oviposition stimulants isolated from Lycopersicon hirsutum
Francisco Bermejo,Alfonso Fernández Mateos,Andrés Marcos Escribano,Rodrigo Martín Lago,Lydia Mateos Burón,María Rodríguez López,R. Rubio Gonzalez +6 more
TL;DR: In this paper, the Ti(III)-promoted radical cyclization of epoxyenone 8 is described as the key step to access the diol 10 as a convenient starting material of the target molecules.