R
R. van Crevel
Researcher at Radboud University Nijmegen
Publications - 53
Citations - 2255
R. van Crevel is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Tuberculosis & Mycobacterium tuberculosis. The author has an hindex of 22, co-authored 53 publications receiving 1929 citations. Previous affiliations of R. van Crevel include University of Oxford & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Non-specific effects of BCG vaccine on viral infections
TL;DR: Evidence for non-specific protection induced by BCG vaccination against viral infections, possible mechanisms of action, and implications for vaccination policies and vaccine discovery are reviewed.
Journal ArticleDOI
Increased Production of Interleukin 4 by CD4+ and CD8+ T Cells from Patients with Tuberculosis Is Related to the Presence of Pulmonary Cavities
R. van Crevel,Elvina Karyadi,F. Preyers,M. Leenders,B.J. Kullberg,R.H.H. Nelwan,J.W.M. van der Meer +6 more
TL;DR: The Th2-type response with increased production of IL-4 in patients with tuberculosis may antagonize host defense and lead to tissue necrosis, and little is known about their role in tissue damage.
Journal Article
Diabetes mellitus is strongly associated with tuberculosis in Indonesia.
Bachti Alisjahbana,R. van Crevel,Edhyana Sahiratmadja,M. Den Heijer,A. Maya,E. Istriana,H. Danusantoso,T. H. M. Ottenhoff,R.H.H. Nelwan,J.W.M. van der Meer +9 more
TL;DR: Diabetes mellitus is strongly associated with TB in young and non-obese subjects in an urban setting in Indonesia, which may have implications for TB control and patient care in this region.
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Rifampicin Reduces Plasma Concentrations of Moxifloxacin in Patients with Tuberculosis
Hanneke M. J. Nijland,Rovina Ruslami,A. Juwono Suroto,David M. Burger,Bachti Alisjahbana,R. van Crevel,Rob E. Aarnoutse +6 more
TL;DR: Coadministration of mox ifloxacin with intermittently administered rifampicin and isoniazid results in reduced moxifl oxacin plasma concentrations, which is most likely the result of induced glucuronidation or sulphation by rifampsicin.
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The role of interferon-gamma in the increased tuberculosis risk in type 2 diabetes mellitus.
J. E. Stalenhoef,Bachti Alisjahbana,Erni J Nelwan,J. van der Ven-Jongekrijg,T. H. M. Ottenhoff,J.W.M. van der Meer,R.H.H. Nelwan,Mihai G. Netea,R. van Crevel +8 more
TL;DR: The data suggest that a defective non-specific immune response in diabetes may contribute to an increased susceptibility to develop tuberculosis.