Showing papers by "Rafal Pawlinski published in 2009"

TL;DR: The results suggest that the levels of TF‐positive MPs can be used as a biomarker for evaluating the risk of disseminated intravascular coagulation in endotoxemia.

TL;DR: Examination of feedback activation of FXI in plasma and in genetically altered mice provides the first evidence that at low TF levels FXI is essential in generating a sufficient ambient level of thrombin to permit embryonic development.

TL;DR: It is shown that inhibition of the TF–factor VIIa (FVIIa) complex with active site-inhibited mouse FVIIa (ASIS) attenuates activation of nuclear factor kappaB (NF-κB) and the expression of inflammatory mediators in a mousemodel of I/R injury and indicates that additional studies using other PAR1 inhibitors are necessary to clarify the role of PAR1.