R
Raja Dey
Researcher at University of Minnesota
Publications - 35
Citations - 1485
Raja Dey is an academic researcher from University of Minnesota. The author has contributed to research in topics: Ring (chemistry) & Binding site. The author has an hindex of 15, co-authored 34 publications receiving 973 citations. Previous affiliations of Raja Dey include Chalmers University of Technology & University of Calcutta.
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Regulation, Signaling, and Physiological Functions of G-Proteins.
TL;DR: In this review, what is known about the regulation, signaling, and physiological functions of G-proteins are summarized and a few less explored areas such as the regulation ofG- Proteins by non-GPCRs and the physiological functions that cannot be easily explained by the known G-protein signaling pathways are focused on.
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Nanomaterials for cancer therapy: current progress and perspectives.
TL;DR: Nanomaterials are materials in the nanorange 1-100nm which possess unique optical, magnetic, and electrical properties as discussed by the authors, and they have been modified for a wide range of cancer therapies to overcome toxicity and lack of specificity.
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Nanoscale assemblies and their biomedical applications
TL;DR: This review focuses on biomedical applications of nanoscale assemblies, such as cell targeting, drug delivery, bioimaging and vaccine development, and the use of virus-like particles and self-assembling polypeptide nanoparticles as new vaccine delivery platforms.
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Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer.
Yongheng Chen,Raja Dey,Lin Chen +2 more
TL;DR: Comparison with previously reported structures of p53 dimer:DNA complexes and a chemically trapped p53 tetramer:DNA complex reveals that DNA binding by the p53 core domain is a cooperative self-assembling process accompanied by structural changes of the p 53 dimer and DNA.
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DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Yongheng Chen,Darren L. Bates,Raja Dey,Po Han Chen,Ana Carolina Dantas Machado,Ite A. Laird-Offringa,Remo Rohs,Lin Chen +7 more
TL;DR: Three crystal structures of the full DNA-binding domain (DBD) of human GATA3 protein, which contains both zinc fingers, in complex with different DNA sites are determined, providing insights into the structure and function of GATA proteins and shed light on the molecular basis of long-range gene regulation.