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Rajesh G. Gonnade

Researcher at Academy of Scientific and Innovative Research

Publications -  47
Citations -  581

Rajesh G. Gonnade is an academic researcher from Academy of Scientific and Innovative Research. The author has contributed to research in topics: Lewis acids and bases & Total synthesis. The author has an hindex of 11, co-authored 47 publications receiving 338 citations. Previous affiliations of Rajesh G. Gonnade include National Chemical Laboratory.

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Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite.

TL;DR: It is shown that potency is manifest via tetrahyropyran ring conformations that are housed in the ribose binding pocket of parasite lysyl tRNA synthetase (KRS), and this work provides a new foundation for focusing on inhibitor stereochemistry as a facet of antimicrobial drug development.