R
Rakesh Tiwari
Researcher at Chapman University
Publications - 139
Citations - 2832
Rakesh Tiwari is an academic researcher from Chapman University. The author has contributed to research in topics: Peptide & Cyclic peptide. The author has an hindex of 27, co-authored 123 publications receiving 2255 citations. Previous affiliations of Rakesh Tiwari include Shiv Nadar University & University of Delhi.
Papers
More filters
Journal ArticleDOI
Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome
Cong Cao,Mengia S. Rioult-Pedotti,Paolo Migani,Crystal J. Yu,Rakesh Tiwari,Keykavous Parang,Mark R. Spaller,Dennis J. Goebel,John Marshall +8 more
TL;DR: Brain-derived neurotrophic factor signaling is defective in Angelman syndrome and can be rescued by disruption of Arc/PSD95 binding.
Journal ArticleDOI
Hyperhomocysteinemia: Impact on Neurodegenerative Diseases
TL;DR: An overview of how far research has gone into understanding the homocysteine imbalance with prognostic, causative and preventive measures in treating neurodegenerative diseases is given.
Journal ArticleDOI
Design and biological evaluation of cell-penetrating peptide-doxorubicin conjugates as prodrugs.
TL;DR: Data suggest that cyclic [W(RW)(4)]-Dox can be used as a potential prodrug for improving the cellular delivery and retention of Dox.
Journal ArticleDOI
Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities
Anil Kumar,Anil Kumar,Israr Ahmad,Bhupender S. Chhikara,Rakesh Tiwari,Deendayal Mandal,Keykavous Parang +6 more
TL;DR: A series of two classes of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates synthesized using click chemistry approach exhibited inhibition of Src kinase and inhibited the cell proliferation of HT-29 and SK-Ov-3.
Journal ArticleDOI
Overcoming Barriers for siRNA Therapeutics: From Bench to Bedside
Muhammad Imran Sajid,Muhammad Imran Sajid,Muhammad Moazzam,Shun Kato,Kayley Yeseom Cho,Rakesh Tiwari +5 more
TL;DR: This review has comprehensively discussed the extracellular barriers, including enzymatic degradation of siRNAs by serum endonucleases and RNAases, rapid renal clearance, membrane impermeability, and activation of the immune system.