Ralph Lennart Brattsand

TL;DR: The findings suggest that the manifestations of inflammation present in the airways of smokers with CB are different in those who have developed obstruction compared with those who has not.

TL;DR: In this article, structure-activity studies were performed in rat models to investigate what influences the type of substitution in the 16α,17α-acetal group and the introduction of fluorine in the 9α- or the 6α,9α-positions have on the topical and the systemic activities.

TL;DR: In this article, the authors present a composition for administration primarily to the respiratory tract when treating and controlling anti-inflammatory conditions comprising liposomes in combination with a compound of the formula I wherein Q is and R1 is a saturated or unsaturated, straight or branched alkyl group with 11-l9 carbon atoms and R is H, -COCH3, -COC2H5, - CO(CH2)2CH3 or -CO(CH 2)3CH3.

TL;DR: BMs and AMs displayed significant differences in both cytokine secretion and susceptibility to regulation by budesonide, and this work confirmed that down-regulation of cytokine production in activated human blood monocytes and alveolar macrophages can be achieved in vitro by treatment with corticosteroids.

TL;DR: The chain-breaking, electron- or hydrogen atom-donating ability of diaryl tellurides seems to be the main reason for their protection against leukocyte-mediated cell damage in Caco-2 cells and in the oxidatively challenged rat kidney and hamster cheek pouch.