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Ramon G. Garcia

Researcher at Mapúa Institute of Technology

Publications -  72
Citations -  812

Ramon G. Garcia is an academic researcher from Mapúa Institute of Technology. The author has contributed to research in topics: Oligonucleotide & Triple helix. The author has an hindex of 15, co-authored 72 publications receiving 729 citations. Previous affiliations of Ramon G. Garcia include Spanish National Research Council.

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New synthetic routes to synthons suitable for 2′-O-allyloligoribonucleotide assembly

TL;DR: The development of a novel synthon based on 2,6-diaminopurine riboside enables short 2'-O-allyl-oligoribonucleotide probes to be synthesized with adenine replaced by 2-aminoadenine, and very stable hybrids with complementary RNA target sequences can be formed.
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Properties of triple helices formed by parallel-stranded hairpins containing 8-aminopurines

TL;DR: Hairpins carrying 8-aminopurines give very stable triple helical structures even at neutral pH, as confirmed by gel-shift experiments, circular dichroism and nuclear magnetic resonance spectroscopy.
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The structural protein p54 is essential for African swine fever virus viability

TL;DR: It is demonstrated that the p54 gene product plays an essential role in virus growth, characterizing for the first time in ASFV an essential virus gene.
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DNA-triplex stabilizing properties of 8-aminoguanine

TL;DR: A DNA-triplex stabilizing purine (8-aminoguanine) is designed based on molecular modeling and synthesized and it is demonstrated that few changes are found in the structure of the triplex due to the presence of this modified base.