Raquel O. Rodrigues

TL;DR: An overview of the microfabrication techniques is given, especially for biomedical applications, as well as a synopsis of some design considerations regarding microfluidic devices.

TL;DR: This review presents recent advances in the development of microfluidic devices to evaluate the mechanical response of individual red blood cells and microbubbles flowing in constriction microch channels and shows the potential of using hyperbolic-shaped microchannels to precisely control and assess small changes in RBC deformability in both physiological and pathological situations.

TL;DR: Recent advances on OoC platforms, particularly on the preclinical validation of nanomaterials designed for cancer, as well as the current challenges and possible future directions for an end-use perspective are discussed.

TL;DR: This work presents a novel integrative microfluidic device able to perform continuous separation of a desired amount of blood cells, without clogging or jamming, and at the same time, capable to assess the deformation index (DI) of both WBCs and RBCs.

TL;DR: The ability of the proposed method to perform cell free layer (CFL) measurements and the formation of microbubbles in continuous blood flow is demonstrated and the high costs and time involved in the production of molds by photolithography are slowed down.