Raquel Silva

TL;DR: The fabrication of microcapsules from an alginate-gelatin crosslinked hydrogel (ADA-GEL) is highlighted and the evaluation of the physico-chemical properties of the new micro Capsules which are relevant for designing suitable microcapsule for tissue engineering are presented.

TL;DR: Viability, attachment, spreading and proliferation of fibroblasts were significantly increased on ADA-GEL hydrogels compared to alginate, and in vitro cytocompatibility of ADA- GEL Hydrogels was found to be increased with increasing gelatin content, indicating thatADA-Gel hydrogel is a promising material for the biomedical applications in tissue-engineering and regeneration.

TL;DR: This paper reviews the fabrication and use of fibrous protein-based hydrogels, with an emphasis on silk, keratin elastin and resilin proteins, and finds them to be one of the most versatile materials for tissue engineering.

TL;DR: Alginate hydrogels covalently crosslinked with gelatin show the highest degree of cell adhesion, spreading, migration, and proliferation, as well as a faster degradation rate, and are therefore a particularly suitable material for microencapsulation.

TL;DR: The composite material showed potential for future applications in bone tissue engineering, and no differences were found in cell viability between ADA-GEL and the composite constructs, proving that the addition of BGNPs did not influence cell fate.