Rashmi Kumari

TL;DR: There was a significant continual decrease in vector immunity titers with time, thereby leading to significant continual increases in the levels of HA-specific humoral and cell-mediated immune responses.

TL;DR: Some of the current usages of AdV vectors and their production methods are emphasized, which have a wide range of applications for different clinical settings.

TL;DR: Evaluated vaccine immunogenicity and efficacy of BAdV-3 vector expressing hemagglutinin (HA) of a H5N1 influenza virus in mice with the intranasal or intramuscular route of inoculation suggest that at least 30-fold dose sparing can be achieved with BAd-H5HA vector compared with HAd- H5HA vaccine vector.

TL;DR: The tumorigenesis of the reck gene is investigated using zebrafish genetic models in both tp53 and ribosomal protein gene mutation background and restoration of the RECK gene in human MPNST cells leads to growth inhibition suggesting that the reactivation of RECK could serve as a potential therapeutic strategy forMPNSTs.

TL;DR: A review of FDA-approved influenza antivirals with their mechanisms of action, and different viral-and host-directed influenza antiviral approaches, including immunomodulatory interventions in clinical development is presented in this article .