Rattiyaporn Kanlaya

TL;DR: Complement activation mediated by NS1 leads to local and systemic generation of anaphylatoxins and SC5b-9, which may contribute to the pathogenesis of the vascular leakage that occurs in patients with DHF/DSS.

TL;DR: Recovery yield and pattern of resolved protein spots were compared among different methods and intra-/inter-individual variabilities were examined, and male urine had greater amount of total protein but provided smaller number of protein spots compared to female urine.

TL;DR: Functional analyses of alterations in actin cytoskeletal assembly and endothelial integrity focusing on adherens junction, tight junction and adhesive molecule after 24-h of DEN-2 infection and simulation of transendothelial migration by PECAM-1 cross-linking suggest alterations may potentially be a molecular basis explaining increased endothelial permeability or vascular leakage in DSS.

TL;DR: The data indicate that oxalate turned on EMT of renal tubular cells that could be prevented by EGCG via Nrf2 pathway, and shed light onto development of novel therapeutics or preventive strategies of renal fibrosis in the future.

TL;DR: Host responses as determined by changes in the cellular proteome of primary human endothelial cells upon infection with dengue virus serotype 2 at a multiplicity of infection (MOI) of 10 for 24 h suggest that various biological processes were triggered in response to d Dengue infection, particularly antiviral IFN and ubiquitin-proteasome pathways.