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Raul C. Urtasun

Researcher at Cross Cancer Institute

Publications -  86
Citations -  4122

Raul C. Urtasun is an academic researcher from Cross Cancer Institute. The author has contributed to research in topics: Misonidazole & Radiation therapy. The author has an hindex of 37, co-authored 86 publications receiving 3945 citations. Previous affiliations of Raul C. Urtasun include University of Alberta & Mayo Clinic.

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Radiobiological characterization of the inactivating events produced in mammalian cells by helium and heavy ions

J.D. Chapman, +3 more
- 01 Jan 1977 - 
TL;DR: The sensitizers, metronidazole, Ro 7-0582, and Ro7-0741, at 5 mM concentration were effective in reducing the OER's of the beams studied by ∼ 55%, ∼ 75% and ∼ 85%, respectively, and such drugs appear to have a potential benefit in radiotherapy planned with heavy ions.
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Single-Arm, Open-Label Phase II Study of Intravenously Administered Tirapazamine and Radiation Therapy for Glioblastoma Multiforme

J. Del Rowe, +6 more
- 13 Mar 2000 - 
TL;DR: Survival in the population treated with radiation and tirapazamine was equivalent to the control population, and patients in RPA class III treated with Radiation Therapy Oncology Group (RTOG) patients with glioblastoma multiforme patients had a longer survival when compared with the historical controls.
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Misonidazole combined with hyperfractionation in the management of malignant glioma

Dorcas Fulton, +9 more
- 01 Sep 1984 - 
TL;DR: Survival was significantly improved for patients treated with MDF compared to patientstreated with CF and the addition of MISO to MDF did not result in further improvement in survival.
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Initial report of the phase I trial of the hypoxic cell radiosensitizer SR-2508.

C.Norman Coleman, +6 more
- 01 Sep 1984 - 
TL;DR: Using a starting dose of 2 g/m2 three times weekly, patients are now being studied on a five week drug schedule to further evaluate predictability of drug toxicity in preparation for clinical trials of drug efficacy.
Journal Article

Peripheral neuropathy related to misonidazole: incidence and pathology.

Raul C. Urtasun, +8 more
- 01 Jun 1978 - 
TL;DR: The human tolerance to multiple dosages of misonidazole (Ro-07-0582) was studied in 28 patients with different types of malignant neoplasias and revealed residual of previous distal axonal degeneration, with some segmental demyelinations and remyelination, which affected both large and small myelinated nerve fibres.