R
Ravi Iyengar
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 297
Citations - 20947
Ravi Iyengar is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Adenylyl cyclase & G protein. The author has an hindex of 69, co-authored 283 publications receiving 19465 citations. Previous affiliations of Ravi Iyengar include City University of New York & Mount Sinai Hospital.
Papers
More filters
Journal ArticleDOI
Emergent Properties of Networks of Biological Signaling Pathways
Upinder S. Bhalla,Ravi Iyengar +1 more
TL;DR: Biochemical signaling networks were constructed with experimentally obtained constants and analyzed by computational methods to understand their role in complex biological processes and raise the possibility that information for "learned behavior" of biological systems may be stored within intracellular biochemical reactions that comprise signaling pathways.
Journal ArticleDOI
G Protein Pathways
TL;DR: The heterotrimeric guanine nucleotide–binding proteins (G proteins) are signal transducers that communicate signals from many hormones, neurotransmitters, chemokines, and autocrine and paracrine factors, which regulate systemic functions such as embryonic development, gonadal development, learning and memory, and organismal homeostasis.
Journal ArticleDOI
Functional atlas of the integrin adhesome
TL;DR: Examination of the adhesome network motifs reveals a relatively small number of key motifs, dominated by three-component complexes in which a scaffolding molecule recruits both a signalling molecule and its downstream target.
Journal ArticleDOI
MAP Kinase Phosphatase As a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network
TL;DR: It is found that the growth factor–stimulated signaling network containing MAPK 1, 2/PKC can operate with one (monostable) or two (bistable) stable states, and MAPK phosphatase may be critical for this flexible response.
Journal ArticleDOI
Complexity in Biological Signaling Systems
TL;DR: The origins of the complex behavior of signaling networks and analytical approaches to deal with the emergent complexity are discussed here.