R
Raymond E. Boissy
Researcher at University of Cincinnati
Publications - 141
Citations - 7767
Raymond E. Boissy is an academic researcher from University of Cincinnati. The author has contributed to research in topics: Melanocyte & Tyrosinase. The author has an hindex of 48, co-authored 139 publications receiving 7254 citations. Previous affiliations of Raymond E. Boissy include Boston Children's Hospital & Cincinnati Children's Hospital Medical Center.
Papers
More filters
Journal ArticleDOI
Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome.
Deborah L. Nagle,Mohammad A. Karim,Elizabeth A. Woolf,Lisa Holmgren,Peer Bork,Donald J. Misumi,Sonja H. McGrail,Barry J. Dussault,Charles M. Perou,Raymond E. Boissy,Geoffrey M. Duyk,Richard A. Spritz,Karen J. Moore +12 more
TL;DR: Analysis of the CHS polypeptide demonstrates that its modular architecture is similar to the yeast vacuolar sorting protein, VPS15, and this work describes the sequence of a human cDNA homologous to mouse beige, identify pathologic mutations and clarify the discrepancies of the previous reports.
Journal ArticleDOI
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
Tomohiro Hakozaki,Ljiljana Minwalla,J. Zhuang,M. Chhoa,A. Matsubara,Kukizo Miyamoto,Amanda Greatens,Greg George Hillebrand,Donald Lynn Bissett,Raymond E. Boissy +9 more
TL;DR: There is a need for the development of skin lightening agents for Asian women and Niacinamide is a possible candidate.
Journal ArticleDOI
Clinical, molecular, and cell biological aspects of Chediak-Higashi syndrome.
TL;DR: Because the beige mouse demonstrates many characteristics similar to those of human CHS patients, including dilution of coat color, recurrent infections, and the presence of giant granules, it is considered the animal homologue of CHS.
Journal ArticleDOI
Mechanisms regulating skin pigmentation: the rise and fall of complexion coloration.
TL;DR: The regulation of processes that control skin complexion coloration is discussed, which includes direct inhibition of tyrosinase and related melanogenic enzymes, regulation of melanocyte homeostasis, alteration of constitutive and facultative pigmentation and down-regulation of melanosome transfer to the keratinocytes.
Journal ArticleDOI
Melanosome transfer to and translocation in the keratinocyte.
TL;DR: Ultraviolet irradiation (UVR) can modulate the process of melanosome transfer from the melanocytes to the keratinocytes and UVR can upregulate expression of PAR‐2 and lectin‐binding receptors and increase phagocytic activity of cultured keratinocyte.