R
Reiko Nishimura
Researcher at Nihon University
Publications - 3
Citations - 433
Reiko Nishimura is an academic researcher from Nihon University. The author has contributed to research in topics: Cytotoxicity & Jurkat cells. The author has an hindex of 3, co-authored 3 publications receiving 378 citations.
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Journal ArticleDOI
Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri
Norihiro Banno,Toshihiro Akihisa,Ken Yasukawa,Harukuni Tokuda,Keiichi Tabata,Yuji Nakamura,Reiko Nishimura,Yumiko Kimura,Takashi Suzuki +8 more
TL;DR: Upon evaluation of 17 compounds, 1-14 and 16-18, and compound 15, semi-synthesized from 14 by acetylation, for their inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, all of the compounds exhibited marked anti-inflammatory activity with a 50% inhibitory dose (ID(50) of 0.05-0.49 mg/ear.
Journal ArticleDOI
Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma.
Reiko Nishimura,Keiichi Tabata,Motoki Arakawa,Yoshihisa Ito,Yumiko Kimura,Toshihiro Akihisa,Hisashi Nagai,Atsuko Sakuma,Hideki Kohno,Takashi Suzuki +9 more
TL;DR: Results suggest that isobavachalcone induces apoptotic cell death in neuroblastoma via the mitochondrial pathway and has no cytotoxicity against normal cells, and may be applicable as an efficacious and safe drug for the treatment of Neuroblastoma.
Journal ArticleDOI
Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells.
Keiichi Tabata,Kou Motani,Noriya Takayanagi,Reiko Nishimura,Satoru Asami,Yumiko Kimura,Motohiko Ukiya,Daisuke Hasegawa,Toshihiro Akihisa,Takashi Suzuki +9 more
TL;DR: Results suggest that xanthoangelol induces apoptotic cell death by activatation of caspase-3 in neuroblastoma and leukemia cells through a mechanism that does not involve Bax/Bcl-2 signal transduction, and may be applicable as an effective drug for treatment of neuroblastomas and leukemia.