Journal ArticleDOI
Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri
Norihiro Banno,Toshihiro Akihisa,Ken Yasukawa,Harukuni Tokuda,Keiichi Tabata,Yuji Nakamura,Reiko Nishimura,Yumiko Kimura,Takashi Suzuki +8 more
TLDR
Upon evaluation of 17 compounds, 1-14 and 16-18, and compound 15, semi-synthesized from 14 by acetylation, for their inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, all of the compounds exhibited marked anti-inflammatory activity with a 50% inhibitory dose (ID(50) of 0.05-0.49 mg/ear.About:
This article is published in Journal of Ethnopharmacology.The article was published on 2006-09-19. It has received 183 citations till now. The article focuses on the topics: Boswellia & Boswellia sacra.read more
Citations
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Current Status of Herbal Drugs in India: An Overview
TL;DR: The global knowledge about Ayurveda and Indian herbals will hopefully be enhanced by information on the evidence-base of these plants, which will yield rich dividends in the coming years.
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Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data.
TL;DR: This review underlines BSE as a promising alternative to NSAIDs, which warrants investigation in further pharmacological studies and clinical trials and presents different perspectives and gives a differentiated insight into the possible mechanisms of action of BSE in humans.
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Natural anti-inflammatory agents for pain relief
TL;DR: Although nonsteroidal medications can be effective, herbs and dietary supplements may offer a safer, and often an effective, alternative treatment for pain relief, especially for long-term use.
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Wound healing and the use of medicinal plants
TL;DR: An extensive survey of literature reporting the use of medical plants and plant-based products for cutaneous wounds describes the active ingredients, bioactivities, clinical uses, formulations, methods of preparation, and clinical value of 36 medical plant species.
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A review of the efficacy of traditional Iranian medicine for inflammatory bowel disease.
TL;DR: The etiology of inflammatory bowel disease (IBD) is not yet known, but many factors such as defects in the immune system, oxidative stress, microbial content in the gastrointestinal tract, nuclear factor (NF)-κB, nitric oxide (NO), cyclooxygenase-2 (Cox-2), and leukotriene B4 (LB4) are thought to play a role in its pathogenesis as discussed by the authors.
References
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Journal ArticleDOI
Mechanism of antiinflammatory actions of curcumine and boswellic acids.
TL;DR: The data suggest that boswellic acids are specific, non-redox inhibitors of leukotriene synthesis either interacting directly with 5-lipoxygenase or blocking its translocation.
Journal Article
Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase.
TL;DR: The data strongly suggest that BAs are specific, nonreducing-type inhibitors of the 5-LO product formation either interacting directly with the5-LO or blocking its translocation.
Journal ArticleDOI
Anti-inflammatory actions of pentacyclic triterpenes.
Hasan Safayhi,E.-R. Sailer +1 more
TL;DR: This survey critically reviews the effects of PTs on proinflammatory mediator signalling pathways and data from experimental animal models and clinical trials to help understand the systemic anti-inflammatory actions of aglycones.
Journal Article
Inhibition by Boswellic Acids of Human Leukocyte Elastase
TL;DR: The data show that the dual inhibition of 5-lipoxygenase and HLE is unique to boswellic acids, and might be the rationale for the putative antiphlogistic activity of acetyl-11-keto-beta-boswellic acid and derivatives.
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Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non-steroidal anti-inflammatory agent.
G B Singh,C K Atal +1 more
TL;DR: In formaldehyde and adjuvant arthritis, AESG produced prominent anti-arthritic activity but no significant effect was observed in cotton pellet-induced granuloma test and it inhibited inflammation induced increase in serum transaminase levels and leucocyte counts but lacked any analgesic or anti-pyretic effects.