https://www.cell.com/neuron/pdf/S0896-6273(01)00317-8.pdf

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Lipid peroxides and human diseases.

Rotavirus gene structure and function.

An apparently new enterovirus was isolated in California from more than 20 patients with central nervous system (CNS) disease during the past four years; one strain was isolated from the brain of a fatal case of encephalitis. The representative BrCr strain had the physicochemical properties of an enterovirus. The human origin of the virus strains was confirmed by the reisolation from the original clinical specimens and the demonstration of increases in neutralizing antibody in patients from whom virus was isolated. Cross-neutralization and immunodiffusion tests indicated that the virus was distinct from the currently recognized enteroviruses of man. A few strains in the group were weakly pathogenic in suckling mice and produced symptoms similar to those produced by group A coxsackieviruses. A number of the strains required treatment with sodium deoxycholate to disaggregate the virus before neutralization could be demonstrated with homologous antiserum.

An Apparently New Enterovirus Isolated from Patients with Disease of the Central Nervous System

Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo: A Novel Therapy for Parkinson's Disease

Pandemic of new type of conjunctivitis.

Relation between subacute myelo-optic neuropathy (s.m.o.n.) and clioquinol: nationwide survey

Experimental vertical transmission of rubella virus in rabbits.

Summary
A recombinant between simian rotavirus, simian agent 11 (SA-11) and bovine rotavirus, neonatal calf diarrhoea virus (NCDV), was obtained by mixed infection of MA-104 cells with NCDV and u.v.-irradiated SA-11 virus, and isolation of a plaque formed in the presence of anti-NCDV serum. The genome of the recombinant contained dsRNA segments 4, 5 and 10 derived from SA-11 virus and segments 1, 2, 3, 6 and 11 derived from NCDV, and segments 7, 8 and 9 of undetermined origin. Polypeptides VP4, VP5, VP7a, VP7b, NCVP1 and NCVP3 were derived from SA-11 virus and polypeptides VP1, VP2, VP3, VP6, VP8, NCVP2a and NCVP2b from NCDV. Haemagglutination of the recombinant was inhibited and its infectivity neutralized by the antiserum against SA-11 virus but not by anti-NCDV serum.

Isolation of a Recombinant between Simian and Bovine Rotaviruses

/pdf/subacute-myelo-optico-neuropathy-a-new-neurological-disease-3mrliulcbx.pdf

Reisaku Kono

Papers

Pandemic of new type of conjunctivitis.

Relation between subacute myelo-optic neuropathy (s.m.o.n.) and clioquinol: nationwide survey

Experimental vertical transmission of rubella virus in rabbits.

Isolation of a Recombinant between Simian and Bovine Rotaviruses

Subacute myelo-optico-neuropathy, a new neurological disease prevailing in Japan.