R
Renata Bujak
Researcher at Gdańsk Medical University
Publications - 13
Citations - 551
Renata Bujak is an academic researcher from Gdańsk Medical University. The author has contributed to research in topics: Metabolomics & Benzoylecgonine. The author has an hindex of 9, co-authored 12 publications receiving 390 citations. Previous affiliations of Renata Bujak include CEU San Pablo University.
Papers
More filters
Journal ArticleDOI
Metabolomics for laboratory diagnostics.
TL;DR: The research strategies and analytical platforms commonly applied in the metabolomics studies are discussed and some limitations and further improvements which should be considered are discussed taking in mind potential applications of metabolomic research and practice.
Journal ArticleDOI
Urine metabolic fingerprinting using LC-MS and GC-MS reveals metabolite changes in prostate cancer: A pilot study.
Wiktoria Struck-Lewicka,Marta Kordalewska,Renata Bujak,Arlette Yumba Mpanga,Marcin Markuszewski,Julia Jacyna,Marcin Matuszewski,Roman Kaliszan,Michał J. Markuszewski +8 more
TL;DR: In this paper, a metabolomics study related to urinary metabolic fingerprinting analyses has been performed in order to scrutinize potential biomarkers that could help in explaining the pathomechanism of the disease and be potentially useful in its diagnosis and prognosis.
Journal ArticleDOI
Blood–brain barrier permeability mechanisms in view of quantitative structure–activity relationships (QSAR)
TL;DR: The data indicate that molecular energy-related descriptors, in combination with the well-known descriptors of lipophilicity may have a supportive value in predicting blood-brain distribution, which is of utmost importance in drug development and toxicological studies.
Journal ArticleDOI
PLS-Based and Regularization-Based Methods for the Selection of Relevant Variables in Non-targeted Metabolomics Data.
TL;DR: This paper is the first to date utilizing the LASSO penalized logistic regression in untargeted metabolomics studies and offers potential improvements over standard linear regression due to the presence of the constrain, which promotes sparse solutions.
Journal ArticleDOI
Metabolomics Reveals Metabolite Changes in Acute Pulmonary Embolism
Renata Bujak,Ana García-Álvarez,Francisco J. Rupérez,Mario Nuño-Ayala,Antonia García,Jesús Ruiz-Cabello,Jesús Ruiz-Cabello,Valentin Fuster,Borja Ibanez,Coral Barbas +9 more
TL;DR: Results presented in this report reveal that combination of LC-MS- and GC- MS-based metabolomics could be a powerful tool for diagnosis and understanding pathophysiological processes due to acute PE.