R
Reuven Bergman
Researcher at Rambam Health Care Campus
Publications - 257
Citations - 9016
Reuven Bergman is an academic researcher from Rambam Health Care Campus. The author has contributed to research in topics: Mycosis fungoides & Population. The author has an hindex of 44, co-authored 253 publications receiving 8162 citations. Previous affiliations of Reuven Bergman include Rappaport Faculty of Medicine & Technion – Israel Institute of Technology.
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Journal ArticleDOI
IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells
Kristine E. Nograles,Lisa C. Zaba,Avner Shemer,Judilyn Fuentes-Duculan,Irma Cardinale,Toyoko Kikuchi,Michal Ramon,Reuven Bergman,James G. Krueger,Emma Guttman-Yassky,Emma Guttman-Yassky +10 more
TL;DR: It is established that T cells could independently express IL-22 even with low expression levels of IL-17, which argues for a functional specialization of T cells such that "T17" and "T22" T-cells may drive different features of epidermal pathology in inflammatory skin diseases.
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Mutations in GALNT3 , encoding a protein involved in O-linked glycosylation, cause familial tumoral calcinosis
Orit Topaz,Orit Topaz,Daniel L. Shurman,Reuven Bergman,Reuven Bergman,Margarita Indelman,Paulina Ratajczak,Mordechai Mizrachi,Mordechai Mizrachi,Ziad Khamaysi,Doron M. Behar,Dan Petronius,Vered Friedman,Israel Zelikovic,Israel Zelikovic,Sharon S. Raimer,Arieh Metzker,Gabriele Richard,Eli Sprecher,Eli Sprecher +19 more
TL;DR: Sequence analysis of GALNT3 identified biallelic deleterious mutations in all individuals with FTC, suggesting that defective post-translational modification underlies the disease.
Journal ArticleDOI
Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to Psoriasis
Emma Guttman-Yassky,Michelle A. Lowes,Judilyn Fuentes-Duculan,Lisa C. Zaba,Irma Cardinale,Kristine E. Nograles,Artemis Khatcherian,Inna Novitskaya,John A. Carucci,Reuven Bergman,James G. Krueger +10 more
TL;DR: Evidence is presented that the IL-23/Th17 axis is largely absent in atopic dermatitis, perhaps accounting for recurrent skin infections in this disease.
Journal ArticleDOI
Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting
Liat Samuelov,Ofer Sarig,Robert M. Harmon,Debora Rapaport,Akemi Ishida-Yamamoto,Ofer Isakov,Jennifer L. Koetsier,Andrea Gat,Ilan Goldberg,Reuven Bergman,Reuven Bergman,Ronen Spiegel,O. Eytan,O. Eytan,Shamir Geller,Sarit Peleg,Noam Shomron,Christabelle S M Goh,Neil J. Wilson,Frances J.D. Smith,Elizabeth Pohler,Michael A. Simpson,W.H. Irwin McLean,Alan D. Irvine,Alan D. Irvine,Mia Horowitz,John A. McGrath,Kathleen J. Green,Eli Sprecher,Eli Sprecher +29 more
TL;DR: The deciphering of the pathogenesis of SAM syndrome substantiates the notion that allergy may result from a primary structural epidermal defect and is linked to a number of genes encoding allergy-related cytokines.
Journal ArticleDOI
Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis
Emma Guttman-Yassky,Michelle A. Lowes,Judilyn Fuentes-Duculan,Julia A. Whynot,Inna Novitskaya,Irma Cardinale,Asifa Haider,Artemis Khatcherian,John A. Carucci,Reuven Bergman,James G. Krueger +10 more
TL;DR: Dermal inflammatory dendritic cells in AD and TNF and iNOS-producing DCs in psoriasis, and/or their regulatory products, may be potential targets for future therapeutic interventions.