A
Asifa Haider
Researcher at Rockefeller University
Publications - 29
Citations - 5010
Asifa Haider is an academic researcher from Rockefeller University. The author has contributed to research in topics: Psoriasis & Tumor necrosis factor alpha. The author has an hindex of 24, co-authored 27 publications receiving 4777 citations. Previous affiliations of Asifa Haider include Novartis & New York Medical College.
Papers
More filters
Journal ArticleDOI
Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells.
Michelle A. Lowes,Toyoko Kikuchi,Judilyn Fuentes-Duculan,Irma Cardinale,Lisa C. Zaba,Asifa Haider,Edward P. Bowman,James G. Krueger +7 more
TL;DR: Th17 cells may be proximal regulators of psoriatic skin inflammation, and warrant further attention as therapeutic targets, and suggest that psoriasis is a mixed Th1 and Th17 inflammatory environment.
Journal ArticleDOI
Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
Wolfgang Hueber,Dhavalkumar D. Patel,Thaddeus P. Dryja,Andrew M Wright,Irina Koroleva,Gerard Bruin,Christian Antoni,Zoe Diana Draelos,Michael H. Gold,Patrick Durez,Paul P. Tak,Juan J. Gomez-Reino,C. Stephen Foster,Rosa Y. Kim,C. Michael Samson,Naomi S. Falk,David S. Chu,David Callanan,Quan Dong Nguyen,Kristine Rose,Asifa Haider,Franco Di Padova +21 more
TL;DR: The results demonstrate that IL-17A participates in psoriasis, rheumatoid arthritis, and uveitis and that the antibody against this cytokine may be an effective therapeutic agent, and warrant larger clinical trials to assess further the safety and efficacy of AIN457.
Journal Article
Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells. Discussion. Commentary
Andrew Blauvelt,Michelle A. Lowes,Toyoko Kikuchi,Judilyn Fuentes-Duculan,Irma Cardinale,Lisa C. Zaba,Asifa Haider,Edward P. Bowman,James G. Krueger +8 more
TL;DR: In this paper, the importance of T helper 17 (Th17) cells in inflammation and autoimmunity is recognized, and they localized Th17 cells predominantly to the dermis of psoriasis skin lesions, confirmed that IL-17 mRNA increased with disease activity, and demonstrated that IL 17 mRNA expression normalized with cyclosporine therapy.
Supplementary Materials for Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
Wolfgang Hueber,Dhavalkumar D. Patel,Thaddeus P. Dryja,Andrew M Wright,Gerard Bruin,Christian Antoni,Michael H. Gold,Patrick Durez,Paul P. Tak,Juan J. Go,C. Stephen Foster,Rosa Y. Kim,C. Michael Samson,Naomi S. Falk,David S. Chu,David Callanan,Asifa Haider +16 more
Journal ArticleDOI
Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis
Emma Guttman-Yassky,Michelle A. Lowes,Judilyn Fuentes-Duculan,Julia A. Whynot,Inna Novitskaya,Irma Cardinale,Asifa Haider,Artemis Khatcherian,John A. Carucci,Reuven Bergman,James G. Krueger +10 more
TL;DR: Dermal inflammatory dendritic cells in AD and TNF and iNOS-producing DCs in psoriasis, and/or their regulatory products, may be potential targets for future therapeutic interventions.