R
Reza Mahjub
Researcher at University of British Columbia
Publications - 7
Citations - 156
Reza Mahjub is an academic researcher from University of British Columbia. The author has contributed to research in topics: Insulin & Diabetes mellitus. The author has an hindex of 4, co-authored 7 publications receiving 105 citations.
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Journal ArticleDOI
Recent advances in applying nanotechnologies for cancer immunotherapy
Reza Mahjub,Sukhdeep Jatana,Suen Ern Lee,Zhu Qin,Griffin Pauli,Meysam Soleimani,Soheil Madadi,Shyh-Dar Li +7 more
TL;DR: This article focuses on recent advances made within the last 5 years in nanoparticle‐based cancer immunotherapy, including peptide‐ and nucleic acid‐based nanovaccines, nanomedicines containing an immunoadjuvant to activate anti‐tumor immunity, nanoparticle delivery of immune checkpoint inhibitors and the combination of the above approaches.
Journal ArticleDOI
The Potential Use of Peptides in Cancer Treatment.
TL;DR: The results obtained in studies presented in this paper indicate that peptides are promising candidates for targeted cancer therapy, and the challenges of using peptide drugs and ways to overcome these limitations are reviewed.
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Potential microRNA-related targets in clearance pathways of amyloid-β: novel therapeutic approach for the treatment of Alzheimer's disease.
TL;DR: An overview on microRNAs that are involved in the Aβ cascade and their inhibitory impact on their target mRNAs whose products participate in Aβ clearance is discussed.
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Effect of insulin-loaded trimethyl chitosan nanoparticles on genes expression in the hippocampus of diabetic rats
Giti Kalantarian,Nasrin Ziamajidi,Roghayeh Abbasalipourkabir,Reza Mahjub,Mohammad Taghi Goodarzi,Massoud Saidijam,Sara Soleimani Asl,Mohammad Jamshidi +7 more
TL;DR: Oral insulin in the form of nanoparticles may have similar effects to injectable insulin in increasing the gene expression of IGF1 and IGF2 in rats treated with insulin-loaded trimethyl chitosan nanoparticles.
Journal ArticleDOI
Effect of insulin-coated trimethyl chitosan nanoparticles on IGF-1, IGF-2, and apoptosis in the hippocampus of diabetic male rats.
Giti Kalantarian,Nasrin Ziamajidi,Reza Mahjub,Mohammad Taghi Goodarzi,Massoud Saidijam,Sara Soleimani Asl,Roghayeh Abbasalipourkabir +6 more
TL;DR: In vivo results showed the efficacy of insulin-coated nanoparticles as well as commercial insulin in compensated weight loss, FBS and protein levels of IGF-1 and IGF-2 in rats with diabetes mellitus.