Ricardo José Tofano

TL;DR: Myokines are protagonists in the complex condition of sarcopenia, which is associated with adverse clinical outcomes in patients with CVD and the discovery of new pathways and the link between myokines and CVD remain a cornerstone toward multifaceted interventions and perhaps the minimization of the damage resulting from muscle loss induced by factors such as atherosclerosis.

TL;DR: In this paper, a review of the crosstalk between adipokines, myokines and hepatokines is presented, which can interfere with homeostatic disorders and can play a role as a potential therapeutic target that can assist in the diagnosis of metabolic syndrome and CVD.

TL;DR: A remarkable prevalence of low concentrations of Vitamin D in patients with cardiovascular risk factors was showed and Vitamin D correlated negatively with glycemia, HbA1C, triglycerides, atherogenic indices, Body Mass Index, and blood pressure.

TL;DR: It is possible to conclude that the use of GB can provide benefits in the prevention and treatment of aging-related conditions.

TL;DR: Both HDL-c and non-HDL-c are associated with insulin resistance, dyslipidemia, atherogenic indices, and obesity and there is a need for randomized clinical intervention trials examining the potential role of non- HDL- c as a possible primary therapeutic target.