Richard Cairns

TL;DR: The TIMI risk score for STEMI captures the majority of prognostic information offered by a full logistic regression model but is more readily used at the bedside, likely to be clinically useful in the triage and management of fibrinolytic-eligible patients with STEMI.

TL;DR: Among patients undergoing cardiac catheterization with planned percutaneous coronary intervention, loading with 60 mg prasugrel resulted in greater platelet inhibition than a 600-mg clopidogrel loading dose.

TL;DR: Intensive statin therapy early after ACS leads to a reduction in clinical events at 30 days, consistent with greater early pleiotropic effects, and in stable patients, intensive statin Therapy provides long-term reduction inclinical events when compared with standard therapy.

TL;DR: Evaluated the efficacy of long-term treatment with gatifloxacin, a bactericidal antibiotic known to be effective against C. pneumoniae in a double-blind, randomized, placebo-controlled trial and no reduction in the rate of cardiovascular events was observed.

TL;DR: A simple risk index based on characteristics easily assessed by any paramedical or clinical personnel captures most of the information from more complex tools, and is likely to be useful in the rapid triage of patients with STEMI outside hospital or on first arrival in the hospital.