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Richard H. Mattson

Researcher at Yale University

Publications -  194
Citations -  18563

Richard H. Mattson is an academic researcher from Yale University. The author has contributed to research in topics: Epilepsy & Anticonvulsant. The author has an hindex of 71, co-authored 190 publications receiving 17901 citations. Previous affiliations of Richard H. Mattson include United States Department of Veterans Affairs & Veterans Health Administration.

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Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures

TL;DR: Overall, carbamazepine and phenytoin are recommended drugs of first choice for single-drug therapy of adults with partial or generalized tonic-clonic seizures or with both.
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How Often Is Medication Taken as Prescribed?: A Novel Assessment Technique

TL;DR: Using a new method with epilepsy as a model, compliance with long-term medications among newly treated and long- term patients is assessed using standard pill bottles with micro-processors in the cap to record every bottle opening as a presumptive dose.
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Characteristics of medial temporal lobe epilepsy: I. Results of history and physical examination

TL;DR: There is a very strong relationship between complicated febrile seizures during early childhood or infancy and the later development of medial temporal lobe epilepsy, which can be a progressive disease as evidenced by silent intervals and progressive elaboration of seizures.
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ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes.

TL;DR: In this article, a 10-member subcommission of the Commission on Therapeutic Strategies of The International League Against Epilepsy (ILAE) evaluated available evidence found through a structured literature review including MEDLINE, Current Contents and the Cochrane Library for all applicable articles from 1940 until July 2005.
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A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. The Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group

TL;DR: Valproate is as effective as carbamazepine for the treatment of generalized tonic-clonic seizures, but carbamazetine provides better control of complex partial seizures and has fewer long-term adverse effects.