R
Riitta Alitalo
Researcher at Helsinki University Central Hospital
Publications - 43
Citations - 2744
Riitta Alitalo is an academic researcher from Helsinki University Central Hospital. The author has contributed to research in topics: Leukemia & Cell culture. The author has an hindex of 25, co-authored 43 publications receiving 2690 citations. Previous affiliations of Riitta Alitalo include Centre national de la recherche scientifique & University of Helsinki.
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Journal Article
FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines.
Katri Pajusola,Olga Aprelikova,Jaana Korhonen,Arja Kaipainen,Liisa Pertovaara,Riitta Alitalo,Kari Alitalo +6 more
TL;DR: The fms-like tyrosine kinase 4 (FLT4) complementary DNA was cloned from a human HEL erythroleukemia cell library by polymerase chain reaction-amplification and the full-length sequence of the predicted FLT4 protein is presented.
Journal Article
Lymphatic Endothelium and Kaposi's Sarcoma Spindle Cells Detected by Antibodies against the Vascular Endothelial Growth Factor Receptor-3
Lotta Jussila,Reija Valtola,Taina A. Partanen,Petri Salven,Päivi Heikkilä,Marja-Terttu Matikainen,Risto Renkonen,Arja Kaipainen,Michael Detmar,Erwin Tschachler,Riitta Alitalo,Kari Alitalo +11 more
TL;DR: Monoclonal antibodies against the extracellular domain of the vascular endothelial growth factor-C receptor that is named VEGFR-3 were found to specifically stain endothelial cells of lymphatic vessels and vessels around tumors such as lymphoma and in situ breast carcinoma.
Journal Article
BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
Luca Tamagnone,Isto Lahtinen,Tuija Mustonen,K Virtaneva,Fiona Francis,Françoise Muscatelli,Riitta Alitalo,C. I. E. Smith,Catharina Larsson,Kari Alitalo +9 more
TL;DR: The BMX gene thus encodes a novel nonreceptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells.
Journal Article
FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter.
Olga Aprelikova,Katri Pajusola,Juha Partanen,Elina Armstrong,Riitta Alitalo,Stacie K. Bailey,Jeannette McMahon,John J. Wasmuth,Kay Huebner,Kari Alitalo +9 more
TL;DR: The cloning of a partial complementary DNA for FLT4, an additional member of this gene family from human leukemia cells, is described, and the results suggest thatFLT4 functions in multiple adult tissues.
Journal ArticleDOI
Putative tyrosine kinases expressed in K-562 human leukemia cells.
TL;DR: Analysis of 359 polymerase chain reaction-amplified cDNA clones led to the identification of 14 different tyrosine kinase-related sequences, which may have a role in the differentiation of megakaryoblastoid differentiation of K-562 cells or in the physiology of platelets.