R
Risto Sankila
Researcher at International Agency for Research on Cancer
Publications - 103
Citations - 10971
Risto Sankila is an academic researcher from International Agency for Research on Cancer. The author has contributed to research in topics: Population & Cancer. The author has an hindex of 54, co-authored 103 publications receiving 10509 citations.
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Journal ArticleDOI
Cancer risk in mutation carriers of DNA-mismatch-repair genes.
M. Aarnio,Risto Sankila,Eero Pukkala,Reijo Salovaara,Lauri A. Aaltonen,A de la Chapelle,Päivi Peltomäki,Jukka-Pekka Mecklin,Heikki Järvinen +8 more
TL;DR: The tumour spectrum associated with germline mutations of DNA‐mismatch‐repair genes involves 8 or more organ sites, suggesting a need to develop methods to screen for extra‐colonic cancer also.
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Estimates of cancer incidence and mortality in Europe in 1995
TL;DR: Cancer incidence and mortality estimates for 1995 are presented for the 38 countries in the four United Nations-defined areas of Europe, using World Health Organization mortality data and published estimates of incidence from national cancer registries to demonstrate the very substantial burden of cancer in Europe, and the scope for prevention.
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Cancer risk in hereditary nonpolyposis colorectal cancer syndrome: later age of onset.
Heather Hampel,Julie A. Stephens,Eero Pukkala,Risto Sankila,Lauri A. Aaltonen,Jukka-Pekka Mecklin,Albert de la Chapelle +6 more
TL;DR: A markedly later age of onset for CRC at 61 y than previously reported (approximately 44 y) is suggested, resulting mainly from a more rigorous method of analysis in which all gene-positive individuals (both affected and unaffected with cancer) are considered.
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Better survival rates in patients with MLH1-associated hereditary colorectal cancer
TL;DR: MLH1-associated colorectal cancer has a natural history different from that of common sporadic coloreCTal cancer, and the better survival rates may be caused by the heavy mutation burden affecting mismatch repair deficient tumor cells.
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Clinical Factors Associated With Merkel Cell Polyomavirus Infection in Merkel Cell Carcinoma
TL;DR: Findings lend support to the hypothesis that viral infection is frequently associated with the pathogenesis of Merkel cell carcinoma.