Rita Pellegrini

TL;DR: Results indicate that MGR3 is directed against a determinant located in the p 185HER2 ligand binding site and may compete with the p185HER2ligand, but is incapable of inducing a complete mitotic signal.

TL;DR: The data suggest that the 67-kd laminin receptor is associated with the metastatic process and supports the hypothesis that hormone therapy might inhibit expression of the receptor, and suggests that hormones may have a regulatory role in the in vivo expression.

TL;DR: Two monoclonal antibodies (mAbs) produced against a human small cell lung carcinoma cell line were found to exhibit a superimposable reactivity on different cell lines and on platelets, and indicated that the two mAbs recognize two epitopes closely localized on the same molecule.

TL;DR: It is reported here that 4-HPR induced apoptosis and/or differentiation in breast cancer cell lines, independent of hormone receptor status and retinoic acid receptor expression, although it was slightly more efficient in inhibiting proliferation of estrogen receptor-positive cells.

TL;DR: Analysis of the ability of SCLC cells to bind radiolabeled laminin and to adhere to laminIn substrata revealed a correlation between these 2 parameters and the expression of VLA‐6 and the 67‐kDa monomeric receptor.