R
Rivka Ravid
Researcher at Netherlands Institute for Neuroscience
Publications - 184
Citations - 18042
Rivka Ravid is an academic researcher from Netherlands Institute for Neuroscience. The author has contributed to research in topics: Temporal cortex & Alzheimer's disease. The author has an hindex of 71, co-authored 184 publications receiving 17038 citations. Previous affiliations of Rivka Ravid include Aix-Marseille University & Imperial College London.
Papers
More filters
Journal ArticleDOI
Broad expression of Toll-like receptors in the human central nervous system
TL;DR: Broad and regulated expression of Toll-like receptors both in vitro and in vivo by human glia cells is revealed.
Journal ArticleDOI
Axonal loss in multiple sclerosis lesions: magnetic resonance imaging insights into substrates of disability.
J.H.T.M. van Waesberghe,Wouter Kamphorst,C. J. A. De Groot,M.A.A. van Walderveen,Jonas A. Castelijns,Rivka Ravid,G. J. Lycklama à Nijeholt,P. van der Valk,Chris H. Polman,Alan J. Thompson,Frederik Barkhof +10 more
TL;DR: Postmortem tissue sampling by using MRI revealed a range of pathology, illustrating the high sensitivity and low specificity of T2‐weighted imaging, and T1 hypointensity and MTR were strongly associated with axonal density, emphasizing their role in monitoring progression in multiple sclerosis.
Journal ArticleDOI
Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
Aileen M. Moloney,Rebecca J. Griffin,Suzanne Timmons,Rosemary O'Connor,Rivka Ravid,Cora O'Neill +5 more
TL;DR: The results show that IGF-1R and IR signalling is compromised in AD neurons and suggest that neurons that degenerate in AD may be resistant to IGF- 1R/IR signalling.
Journal ArticleDOI
Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis
M.A.A. van Walderveen,Wouter Kamphorst,P. Scheltens,J.H.T.M. van Waesberghe,Rivka Ravid,J. Valk,Chris H. Polman,Frederik Barkhof +7 more
TL;DR: It is concluded that, in a limited sample, hypointense lesions seen on T1-weighted SE MR images are associated histopathologically with severe tissue destruction, including axonal loss.
Journal ArticleDOI
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease
Keith D. Coon,Amanda J. Myers,David Craig,Jennifer Webster,John V. Pearson,Diane Hu Lince,Victoria Zismann,Thomas G. Beach,Doris G. Leung,Leslie Bryden,Rebecca F. Halperin,Lauren Marlowe,Mona Kaleem,Douglas G. Walker,Rivka Ravid,Christopher B. Heward,Joseph Rogers,Andreas Papassotiropoulos,Andreas Papassotiropoulos,Eric M. Reiman,John Hardy,Dietrich A. Stephan +21 more
TL;DR: This study provides empirical support for the suggestion that the APOE locus is the major susceptibility gene for late-onset AD in the human genome, with an OR significantly greater than any other locus in thehuman genome.