Robert DeLong

TL;DR: A genomic screen and follow-up analysis to identify potential AutD susceptibility loci and identified eight promising regions on chromosomes 2, 3, 7, 15, 18, 19, and X, which overlap previously reported peak linkage areas.

TL;DR: It is reported that SPSMA and CMT2C are allelic disorders caused by mutations in the gene encoding the transient receptor potential cation channel, subfamily V, member 4 (TRPV4), implying a pathogenic mechanism and possible options for therapy for these disorders.

TL;DR: Data support evidence for a gene on chromosome 2 contributing to risk of AutD, and they suggest that phenotypic homogeneity increases the power to find susceptibility genes for AutD.

TL;DR: It is suggested that an important subgroup of autistic spectrum disorders may be related etiologically to familialmajor affective disorders, and may represent the early‐life onset of a severe phenotype of major affective, particularly bipolar, disease.

TL;DR: The concept that ASD in some cases may be etiologically related to bipolar affective disorder or major depression and no identified neurological disorder is supported.