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Robert E. Kleiger

Researcher at Washington University in St. Louis

Publications -  78
Citations -  6863

Robert E. Kleiger is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Myocardial infarction & Heart rate variability. The author has an hindex of 32, co-authored 78 publications receiving 6669 citations. Previous affiliations of Robert E. Kleiger include St. Louis Children's Hospital & Barnes-Jewish Hospital.

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Journal ArticleDOI

Outcomes in patients with acute non-Q-wave myocardial infarction randomly assigned to an invasive as compared with a conservative management strategy. Veterans Affairs Non-Q-Wave Infarction Strategies in Hospital (VANQWISH) Trial Investigators

William E. Boden, +11 more
- 18 Jun 1998 - 
TL;DR: Patients assigned to the invasive strategy had worse clinical outcomes during the first year of follow-up, and patients assigned to a conservative strategy had better clinical outcomes During an average follow- up of 23 months.
Journal ArticleDOI

Heart rate variability: a measure of cardiac autonomic tone.

Phyllis K. Stein, +3 more
- 01 May 1994 - 
TL;DR: Analysis of HRV based on routine 24-hour Holter recordings provides a sensitive, noninvasive measurement of autonomic input to the heart and time domain measures can be used as surrogates for frequency domain measures which may simplify future studies.
Journal ArticleDOI

Insights from the Study of Heart Rate Variability

Phyllis K. Stein, +1 more
- 01 Jan 1999 - 
TL;DR: HRV in combination with other risk stratifiers, e.g. ejection fraction, can identify cardiac patients at especially high risk of mortality and many but not all interventions associated with increased HRV are also associated with better survival rates.
Journal ArticleDOI

Outcomes in Patients with Acute Non-Q-Wave Myocardial Infarction Randomly Assigned to an Invasive as Compared with a Conservative Management Strategy

William E. Boden, +10 more
- 01 Oct 1999 - 
TL;DR: Most patients with non-Q-wave myocardial infarction do not benefit from routine, early invasive management consisting of coronary angiography and revascularization, and a conservative, ischemia-guided initial approach is both safe and effective.
Journal ArticleDOI

Time domain measurements of heart rate variability.

Robert E. Kleiger, +3 more
- 01 Aug 1992 - 
TL;DR: Assessment of HRV through time domain variables is a simple and practical method of assessing autonomic function that can be used to assess the effects of drugs and other interventions, including exercise and psychological and physical stress on cardiac autonomic tone.