Showing papers by "Robert I. Scheinman published in 2006"

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Journal Article•DOI•

AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix.

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Yunxia Tao¹, Rene Kupfer¹, Benjamin J. Stewart¹, Cheryll Williams-Skipp¹, Christopher K. Crowell¹, Dhavalkumar D. Patel², Steven Sain³, Robert I. Scheinman¹ - Show less +4 more•Institutions (3)

Anschutz Medical Campus¹, University of North Carolina at Chapel Hill², University of Colorado Denver³

01 Feb 2006-Molecular Immunology

TL;DR: A transrepression assay is used to demonstrate that AIRE interacts with multiple components of the transcription complex including a novel interaction with the UBA domain protein, GBDR1, which suggests thatAIRE responsive genes may be localized to specific regions of the genome.

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40 citations